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Michael Smout

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Senior Research Associate

James Cook University Cairns Campus

Australia

Research Interests

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Recent Grants

Grant: Close

UHEAL

Open Date: 2019-01-01

Close Date: 2021-01-01

Grant: Close

Targeting parasite-host communication to combat liver fluke-induced bile duct cancer

Open Date: 2018-01-01

Close Date: 2023-01-01

Grant: Close

Liver fluke growth factor heals wounds

Open Date: 2017-08-01

Close Date: 2018-07-01

Grant: Close

Understanding the granulin growth factor secreted by the infectious carcinogenic liver fluke, Opisthorchis viverrini, and potential as a treatment for chronic diabetic wounds

Open Date: 2016-01-01

Close Date: 2016-01-01

Grant: Close

Exploiting a wound healing helminth granulin protein to treat diabetic ulcers

Open Date: 2016-01-01

Close Date: 2017-01-01

Articles (14)

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2023

Collaborators (9)

Casey Powers

Staff Scientist for Education and Proteomics

Stanford University

UNITED STATES

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Naphak Modhiran

The University of Queensland

AUSTRALIA

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Norelle L. Daly

James Cook University

AUSTRALIA

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Rozita Takjoo

Teaching Assistant

James Cook University

AUSTRALIA

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Michael Liddell

Assoc. Professor

James Cook University

AUSTRALIA

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Joshua Santarpia

University of Nebraska Medical Center

UNITED STATES

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Alex Loukas

Distinguished Professor

James Cook University Cairns Campus

AUSTRALIA

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Mariusz Skwarczynski

A/Prof

University of Queensland

AUSTRALIA

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Paul J. Brindley

Professor

George Washington University

UNITED STATES

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Michael Smout

Research Interests

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Recent Grants

Articles (14)

Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion

Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells

The Anthelmintic Activity of Stonefish (Synanceia spp.) Ichthyocrinotoxins and Their Potential as Novel Therapeutics

The C-terminal region of Opisthorchis viverrini granulin-1 promotes cell proliferation in the absence of regular secondary structure

Development of an efficacious oral peptide vaccine against infection with the carcinogenic liver fluke Opisthorchis viverrini

Genetically modified helminths as pharmaceutical biofactories

Topological isomers of a potent wound healing peptide: Structural insights and implications for bioactivity

Mechanistic insights into liver-fluke-induced bile-duct cancer

Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide-directed β-hairpin fold

Identification of an inter-cysteine loop potentially involved in the activity of Opisthorchis viverrini-granulin-1

Rapid and permanent cytotoxic effects of venom from Chiropsella bronzie and Malo maxima on human skeletal and cardiac muscle cells

Inter-species variation in stonefish (Synanceia spp.) ichthyocrinotoxins; an ecological perspective

Optimizing the xWORM assay for monitoring hookworm larvae motility

Stonefish (Synanceia spp.) Ichthyocrinotoxins: An ecological review and prospectus for future research and biodiscovery

Collaborators (9)

Casey Powers

Naphak Modhiran

Norelle L. Daly

Rozita Takjoo

Michael Liddell

Joshua Santarpia

Alex Loukas

Mariusz Skwarczynski

Paul J. Brindley

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