Michael Trauner

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Professor of Medicine and Chair of Gastroenterology and Hepatology

Medical University of Vienna

Austria

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About

Professor Michael Trauner is the Chair of Gastroenterology and Hepatology at the Medical University of Vienna, Austria. His research primarily focuses on liver diseases, with recent publications addressing diagnostic implications of spleen-to-liver stiffness ratios, neutrophil extracellular traps in chronic liver disease, and the impact of smoking on inflammation and cancer risk in cirrhosis patients. He also explores therapeutic targeting of bile acid circulation and the effectiveness of transjugular intrahepatic portosystemic shunts in clinical settings.

Recent Grants

Grant: Close

RORγt and EGR1 – new potential therapy targets to treat cholestatic liver disease?

Open Date: 2021-01-01

Close Date: 2023-01-01

Grant: Close

Diagnosis and risk stratification of liver diseases using deep learning based on routine clinical data

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Open

Lipid hydrolysis pathways in the progression of cholestatic and metabolic liver disease

Open Date: 2019-01-01

Close Date: 2027-01-01

Grant: Close

Di Mi Liv - Dietary Modulation of intestinal microbiota as Trigger of liver health: role of bile acids

Open Date: 2018-01-01

Close Date: 2021-01-01

Grant: Close

LITMUS: „Liver Investigation - Testing Marker Utility in Steatohepatitis

Open Date: 2017-01-01

Close Date: 2023-01-01

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Professor of Biochemistry

Medical University of Graz

AUSTRIA

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Tomáš Macháček

Assistant Professor

Charles University

CZECH REPUBLIC

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Entcho Klenske

Medical University of Vienna

AUSTRIA

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Thomas Reiberger

Medical University of Vienna

AUSTRIA

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Michael Trauner

Research Interests

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About

Recent Grants

Articles (30)

Benefits and challenges to therapeutic targeting of bile acid circulation in cholestatic liver disease

Diagnostic and Clinical Implications of High Spleen-To-Liver Stiffness Ratio in MASH-A Prospective, Comparative Study.

Neutrophil Extracellular Traps Are Not Linked to Decompensation, ACLF, or Death in Clinically Stable Patients With ACLD.

Smoking Aggravates Inflammation, Fibrogenesis, Angiogenesis and Cancer Risk in Patients With Cirrhosis.

Benefits and challenges to therapeutic targeting of bile acid circulation in cholestatic liver disease.

Bile acid signaling in MASLD: from pathogenesis to therapeutic applications.

Prevalence of fibrosis and applicability of lab-based non-invasive tests from primary to tertiary care.

Loss of bile salt export pump (Bsep/Abcb11) ameliorates toxin-induced hepatic fibrosis via suppression of hepatocellular JNK signaling and HSC activation.

Effectiveness of controlled-expansion transjugular intrahepatic portosystemic shunt (CX-TIPS) in an interdisciplinary setting at a large tertiary center.

Erratum to 'Inhibition of ATGL alleviates MASH via impaired PPARa signalling that favours hydrophilic bile acid composition in mice' [J Hepatol 82 (2025) 658-675].

Prevalence and prognostic value of zinc and selenium deficiency in advanced chronic liver disease

High histamine levels are associated with acute‐on‐chronic liver failure and liver‐related death in patients with advanced chronic liver disease

Evolution of liver function during immune checkpoint inhibitor treatment for hepatocellular carcinoma

Impact of Bowel Preparation Quality on Colonoscopy Findings and Colorectal Cancer Deaths in a Nation-Wide Colorectal Cancer Screening Program

Letter: Fibrates may be safe and effective in patients with primary biliary cholangitis and decompensated cirrhosis—Authors' reply

Rapid improvement of hepatic steatosis and liver stiffness after metabolic/bariatric surgery: a prospective study.

Mortality from upper gastrointestinal tumors in colorectal cancer screening patients.

Secondary bile acids in portal blood contribute to liver regeneration in a rat model of partial hepatectomy.

Polyp size is associated with colorectal cancer death across histologic polyp subtypes: a retrospective study of a screening colonoscopy registry.

Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis.

Transversal psoas muscle thickness measurement is associated with response and survival in patients with HCC undergoing immunotherapy

Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase

Detection of high-risk polyps at screening colonoscopy indicates risk for liver and biliary cancer death.

Bsep/Abcb11 knockout ameliorates Schistosoma mansoni liver pathology by reducing parasite fecundity.

Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome.

GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2<sup>-/-</sup> Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling.

Miniseries: Established pharmacological targets for NASHFXR agonists in NASH treatment.

Gas6 in chronic liver disease-a novel blood-based biomarker for liver fibrosis.

Diabetes impairs the haemodynamic response to non-selective betablockers in compensated cirrhosis and predisposes to hepatic decompensation.

Diagnosis of functional strictures in patients with primary sclerosing cholangitis using hepatobiliary contrast-enhanced MRI: a proof-of-concept study.

Collaborators (15)

Paul Dawson

Michael Schwarz

Laura Liesinger

Tobias Meischl

Georg Semmler

Alessandra Riva

Lukas Hartl

Lorenz Balcar

Rudolf E. Stauber

Luciano Adorini

Mohamed bouattour

Dagmar Kratky

Tomáš Macháček

Entcho Klenske

Thomas Reiberger

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