Paolo Paoli

Associate Professor

University of Florence

Italy

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About

Dr. Paolo Paoli is an Associate Professor at the University of Florence, Italy. His research primarily focuses on the molecular mechanisms of enzyme modulation and the development of novel therapeutic agents, as evidenced by his recent articles on glucocerebrosidase inhibitors and iminosugar derivatives. He also explores the effects of dietary components on health and milk quality, integrating biochemistry with agricultural sciences.

Articles (15)

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2025

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2025

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2025

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (19)

Simone Luti

University of Florence

ITALY

Paolo Paoli

Research Interests

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Articles (15)

Molecular Basis of Pseudomonas syringae pv actinidiae Levansucrase Inhibition by a Multivalent Iminosugar

Acetal functionalized iminosugars for targeting β-glucocerebrosidase modulation

Rational design and synthesis of novel N-benzylindole-based epalrestat analogs as selective aldose reductase inhibitors: An unexpected discovery of a new glucose-lowering agent (AK-4) acting as a mitochondrial uncoupler

Iminosugar‐Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers

Effect of Bovine Milk Peptides on Cell Inflammation, Proliferation and Differentiation: Milk Potential Benefits Are Preserved in an Unconventional Cow Feeding Strategy

Rumen microbial community and milk quality in Holstein lactating cows fed olive oil pomace as part in a sustainable feeding strategy

Light‐Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones

Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge <i>Dysidea</i> <i>avara</i>

Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS)

Synthesis of a New β-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis

Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian Clavelina lepadiformis

Photoswitchable inhibitors of human β-glucocerebrosidase

Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs

3,4,5‐Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers

In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B

Collaborators (19)

Simone Luti

Luigia Pazzagli

Federica Mannelli

Roberta Moschini

Martina Cacciarini

Marcello Casertano

francesco balestri

amelia morrone

ARIANNA BUCCIONI

Marialuisa Menna

Macarena Martínez-Bailén

Alessandra Modesti

ANTONELLA DEL CORSO

MARIO CAPPIELLO

Concetta IMPERATORE

Francesca Cardona

Marta Ferraroni

Sara Campigli

Camilla Matassini

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