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Paolo Paoli

Associate Professor

University of Florence

Italy

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Research Interests

Biochemistry

60%

Food Science

20%

Bioactive Compound

30%

Enzyme Engineering

30%

Chemical Biology

30%

Glycobiology

30%

Animal Nutrition

20%

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Articles15

Molecular Basis of Pseudomonas syringae pv actinidiae Levansucrase Inhibition by a Multivalent Iminosugar

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Year:

2025

Acetal functionalized iminosugars for targeting β-glucocerebrosidase modulation

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Year:

2025

Rational design and synthesis of novel N-benzylindole-based epalrestat analogs as selective aldose reductase inhibitors: An unexpected discovery of a new glucose-lowering agent (AK-4) acting as a mitochondrial uncoupler

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Year:

2025

Iminosugar‐Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers

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Year:

2024

Effect of Bovine Milk Peptides on Cell Inflammation, Proliferation and Differentiation: Milk Potential Benefits Are Preserved in an Unconventional Cow Feeding Strategy

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Year:

2023

Rumen microbial community and milk quality in Holstein lactating cows fed olive oil pomace as part in a sustainable feeding strategy

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Year:

2023

Light‐Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones

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Year:

2023

Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge <i>Dysidea</i> <i>avara</i>

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Year:

2023

Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS)

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Year:

2023

Synthesis of a New β-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis

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Year:

2022

Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian Clavelina lepadiformis

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Year:

2022

Photoswitchable inhibitors of human β-glucocerebrosidase

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Year:

2022

Identifying Human PTP1B Enzyme Inhibitors from Marine Natural Products: Perspectives for Developing of Novel Insulin-Mimetic Drugs

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Year:

2022

3,4,5‐Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers

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Year:

2022

In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications—A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B

Article Link

Year:

2021

Collaborators19

Simone Luti

University of Florence

ITALY

Luigia Pazzagli

University of Florence

ITALY

Federica Mannelli

University of Florence

ITALY

Roberta Moschini

University of Pisa

ITALY

Martina Cacciarini

ITALY

Marcello Casertano

Assistant Professor

University of Naples Federico II

ITALY

francesco balestri

professore associato

Università degli Studi di Roma Tor Vergata Dipartimento di Biologia

ITALY

amelia morrone

associated professor

University of Florence

ITALY

ARIANNA BUCCIONI

Associate Professor

University of Florence

ITALY

Marialuisa Menna

ITALY

Macarena Martínez-Bailén

SPAIN

Alessandra Modesti

University of Florence

ITALY

ANTONELLA DEL CORSO

University of Pisa

ITALY

MARIO CAPPIELLO

Associate Professor

University of Pisa

ITALY

Concetta IMPERATORE

University of Naples Federico II

ITALY

Francesca Cardona

ITALY

Marta Ferraroni

University of Florence

ITALY

Sara Campigli

University of Florence

ITALY

Camilla Matassini

ITALY

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