Peter Czabotar

Walter and Eliza Hall Institute of Medical Research

Australia

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Articles (10)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Collaborators (11)

Rachel Uren

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Brian Smith

Professor

La Trobe University

AUSTRALIA

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Laura Dagley

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Agnes Wingyan Wong

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Jani Reddy Bolla

Stipendiary Lecturer in Biochemistry

University of Oxford New College

UNITED KINGDOM

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David Huang

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Ruth Kluck

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Kym Lowes

Head, Screening Lab

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Brad Sleebs

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Ruitao Jin

La Trobe University

AUSTRALIA

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Fiona Brown

MONASH UNIVERSITY

AUSTRALIA

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Peter Czabotar

Research Interests

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Articles (10)

Computational design of potent and selective binders of BAK and BAX

The BCL-2 protein family: from discovery to drug development

Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

Differential regulation of BAX and BAK apoptotic activity revealed by small molecules

Acquired BCL2 variants associated with venetoclax resistance in acute myeloid leukemia

A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis

Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling

Ion currents through Kir potassium channels are gated by anionic lipids

Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation

Collaborators (11)

Rachel Uren

Brian Smith

Laura Dagley

Agnes Wingyan Wong

Jani Reddy Bolla

David Huang

Ruth Kluck

Kym Lowes

Brad Sleebs

Ruitao Jin

Fiona Brown

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