Peter-Leon Hagedoorn

Delft University of Technology

Netherlands

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Articles (24)

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2025

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2025

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2025

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2025

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2025

This study presents a three-step one pot enzymatic cascade for the synthesis of a δ-lactone. This combination of enzymes can also be applied for the synthesis of the statin side chain.

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (17)

Duncan G. G. McMillan

Delft University of Technology

NETHERLANDS

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Simona Huwiler

University of Zurich

SWITZERLAND

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Yaiza Gonzalez-Garcia

Delft University of Technology

NETHERLANDS

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Ulf Hanefeld

Delft University of Technology

NETHERLANDS

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Dirk Tischler

Ruhr-Universität Bochum

GERMANY

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G. Matthias Ullmann

University of Bayreuth

GERMANY

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Rob Schmitz

Delft University of Technology

NETHERLANDS

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Jianyu Li

University of Freiburg

GERMANY

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Stefan Weber

Professor

University of Freiburg

GERMANY

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Allison Elizabeth Wolder

Delft University of Technology

NETHERLANDS

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Kristina Djanashvili

Delft University of Technology

NETHERLANDS

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Caroline Paul

Assistant Professor

Delft University of Technology

NETHERLANDS

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Iulian Apachitei

Assistant Professor

Delft University of Technology

NETHERLANDS

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Kourosh Honarmand Ebrahimi

King’s College London

UNITED KINGDOM

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Wilfred R. Hagen

Emeritus Professor of Enzymology

Delft University of Technology

NETHERLANDS

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Antonio J. Pierik

Full Professor

Technische Universität Kaiserslautern

GERMANY

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Martin Pabst

Associate Professor and Supervisor MS facility

NETHERLANDS

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Peter-Leon Hagedoorn

Research Interests

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Articles (24)

Role of the Active Site Heme and Tyrosine in Styrene Oxide Isomerase’s Natural Isomerase and Unnatural Peroxidase and Peroxygenase Activity

Functional characterization and membrane localization of the styrene oxide isomerase from Rhodococcus opacus 1CP and Zavarzinia compransoris Z-1155

Chanoclavine synthase operates by an NADPH-independent superoxide mechanism

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

Tungsten containing aldehyde oxidoreductase (AOR)-family enzymes; past, present and future production strategies

Enzymatic cascade of DERA and ADH for lactone synthesis

The metal cofactor: stationary or mobile?

Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase

Immobilization of Oleate Hydratase on Solid Supports

Enzymatic cascade of DERA and ADH for lactone synthesis

Organochlorides Mediate Oxidation Reactions Induced by Low Dose Ionizing Radiation

Asymmetric Monoreduction of α,β-Dicarbonyls to α-Hydroxy Carbonyls by Ene Reductases

Enhancing Magnetic Hyperthermia Efficiency in Pd/Fe-Oxide Hybrid Nanoparticles through Mn-Doping

Enzymatic Birch Reduction via Hydrogen Atom Transfer at an Aqua-Tungsten-bis-Metallopterin Cofactor

Can a Hydroxynitrile Lyase Catalyze an Oxidative Cleavage?

Enzymatic S-Methylation of Thiols Catalyzed by Different O-Methyltransferases

Fighting Antibiotic-Resistant Bacterial Infections by Surface Biofunctionalization of 3D-Printed Porous Titanium Implants with Reduced Graphene Oxide and Silver Nanoparticles

Iron–sulfur clusters as inhibitors and catalysts of viral replication

Substrate Induced Movement of the Metal Cofactor between Active and Resting State

Substrate Induced Movement of the Metal Cofactor between Active and Resting State

Isothermal titration calorimetric assessment of lignin conversion by laccases

Batch and Flow Nitroaldol Synthesis Catalysed by Granulicella tundricola Hydroxynitrile Lyase Immobilised on Celite R-633

Engineering of continuous bienzymatic cascade process using monolithic microreactors – In flow synthesis of trehalose

Isothermal Titration Calorimetry in Biocatalysis

Collaborators (17)

Duncan G. G. McMillan

Simona Huwiler

Yaiza Gonzalez-Garcia

Ulf Hanefeld

Dirk Tischler

G. Matthias Ullmann

Rob Schmitz

Jianyu Li

Stefan Weber

Allison Elizabeth Wolder

Kristina Djanashvili

Caroline Paul

Iulian Apachitei

Kourosh Honarmand Ebrahimi

Wilfred R. Hagen

Antonio J. Pierik

Martin Pabst

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