Philip Dunne

Reader in Molecular Pathology and Early Detection

United Kingdom

Research Interests

Explore related searches

Professors in United Kingdom Professors in Immunology Immunology professors in United Kingdom

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Dr. Philip Dunne is a Reader in Molecular Pathology and Early Detection at Queen's University Belfast School of Medicine Dentistry and Biomedical Sciences. His research focuses on colorectal cancer, including the analysis of IDH1 and IDH2 mutations, tumor purity assessment using deep learning, and the implications of colonic fidelity loss in cancer metastasis. Additionally, his work encompasses areas such as the restoration of NOX4 signaling in diabetes-related vascular dysfunction and the development of machine learning models to predict responses to radiation in rectal cancer.

Articles (20)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (29)

Emma M. Kerr

UNITED KINGDOM

Philip Dunne

Research Interests

Explore related searches

Contact this professor

About

Articles (20)

Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis

Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer

Loss of colonic fidelity enables multilineage plasticity and metastasis

Restoration of NOX4 signalling reverses endothelial colony-forming cell angiogenic dysfunction associated with experimental and clinical diabetes

Targeting the PREX2/RAC1/PI3Kβ signaling axis confers sensitivity to clinically relevant therapeutic approaches in melanoma

Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis

Unveiling impaired vascular function and cellular heterogeneity in diabetic donor-derived vascular organoids

Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors.

Dual gene set enrichment analysis (dualGSEA); an R function that enables more robust biological discovery and pre-clinical model alignment from transcriptomics data

Tumor-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signaling

PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia

Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer

β-catenin drives butyrophilin-like molecule loss and γδ T-cell exclusion in colon cancer.

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.

Erratum: Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia (Cell Stem Cell (2022) 29(8) (1213–1228.e8), (S1934590922003034), (10.1016/j.stem.2022.07.008))

Spend less to achieve more: Economic analysis of intermittent versus continuous cetuximab in KRAS wild-type patients with metastatic colorectal cancer

Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.

Global Colorectal Cancer Research, 2007-21: Outputs and Funding.

Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data.

Collaborators (29)

Emma M. Kerr

Declan French

Livio Trusolino

Nicholas West

Ignacio Soriano

Noemi Lois

Patrizia Cammareri

Assya Legrini

Eduard Batlle

Aideen Ryan

Ultan McDermott

Oliver Treacy

Felicity Lamrock

Hojjat Naderi-Meshkin

Gabriel Valbuena

Leslie Samuel

Timothy Stanley Maughan

Arafath Kaja Najumudeen

Lingfang Zeng

Thomas Ritter

Alberto Bardelli

Owen J. Sansom

David J. Grieve

Dustin Flanagan

Kim De Veirman

Reinhold J. Medina

David Sebag-Montefiore

Andrew A. W. Yacoub

Hayley L. Belnoue-Davis

Make your next move.