Roman Fischer

Head of Advanced Proteomics Facility/Associate Professor

University of Oxford

United Kingdom

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About

Roman Fischer is an Associate Professor and the Head of the Advanced Proteomics Facility at the University of Oxford, UK. His research focuses on proteomics and its application in understanding various biological processes and disorders, including mechanisms of hypoxia, cell cycle dynamics, and amyloid pathology. Recent publications include studies on the effects of acidosis on HIF-1α stabilization and insights into islet adaptations during human pregnancy.

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Collaborators (15)

Andrew Castle

University of Oxford

UNITED KINGDOM

Roman Fischer

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Articles (20)

ATR-hippo drives force signaling to nuclear f-actin and links mechanotransduction to neurological disorders

A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics

Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation

Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes

Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution.

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair

A novel method to quantify fibrin–fibrin and fibrin–α<sub>2</sub>-antiplasmin cross-links in thrombi formed from human trauma patient plasma

A role for vessel-associated extracellular matrix proteins in multiple sclerosis pathology.

A Hybrid Electrospun-Extruded Polydioxanone Suture for Tendon Tissue Regeneration

SARS-CoV-2 mutations affect antigen processing by the proteasome to alter CD8+ T cell responses

Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation

Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

Advancing mechanistic understanding and biomarker development in amyotrophic lateral sclerosis

A modified density gradient proteomic-based method to analyze endolysosomal proteins in cardiac tissue

Proteomic Signature of Dysfunctional Circulating Endothelial Colony‐Forming Cells of Young Adults

Detection and quantification of novel C‐terminal TDP‐43 fragments in ALS‐TDP

Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

Collaborators (15)

Andrew Castle

Jonathan Ian Spencer

Rajesh Thakker

Amit Kumar Mandal

manu vatish

Benedikt Kessler

Jillian Simon

Tímea Feller

Alexander Hasson

David Sims

Simon Buczacki

George Tofaris

Francis Szele

Francesca M. Buffa

Hongbin Yang

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