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Sang-Han Lee

Professor, Director

Kyungpook National University

South Korea

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Research Interests

Biochemistry

40%

Pharmaceutical Chemistry

40%

Phytochemical

90%

Antioxidant Activity

80%

Natural Products Chemistry

50%

Antioxidant Research

40%

Metabolomic

30%

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Recent Grants

Grant: Close

Development of Food Ingredients for Inner-beauty Purpose

Open Date: 2014-05-01

Close Date: 2017-04-01

Articles25

Comparative Metabolite Profiling of Antarctic and Korean Mosses: Insights into Adaptation Mechanisms of Antarctic Moss Species

Article Link

Year:

2025

In silico analysis of dual tyrosinase and elastase inhibition by bioactive ingredients from Gardenia jasminoides seeds

Article Link

Year:

2025

Physicochemical and sensory evaluation of additive-free hot-air dried applemango (Mangifera indica L. var. Irwin) fruit leathers

Article Link

Year:

2025

Research Progress on Anti-Aging with Natural Products: From Pathway Modulation to AI-Driven Discovery

Article Link

Year:

2025

Betulinic Acid-Enriched Dillenia indica L. Bark Extract Attenuates UVB-Induced Skin Aging via KEAP1-Mediated Antioxidant Pathways

Article Link

Year:

2025

γ-Mangosteen, an autophagy enhancer, prevents skin-aging via activating KEAP1/NRF2 signaling and downregulating MAPKs/AP-1/NF-κB-mediated MMPs

Article Link

Year:

2024

RSM- and ANN-Based Multifrequency Ultrasonic Extraction of Polyphenol-Rich Sargassum horneri Extracts Exerting Antioxidative Activity via the Regulation of MAPK/Nrf2/HO-1 Machinery

Article Link

Year:

2024

Biological activities, identification, method development, and validation for analysis of polyphenolic compounds in Nymphaea rubra flowers and leaves by UHPLC‐Q‐cIM‐TOF‐MS and UHPLC‐TQ‐MS

Article Link

Year:

2024

Development of a rapid screening method utilizing 2D LC for effect-directed analysis in the identification of environmental toxicants

Article Link

Year:

2024

Glycoprotein from Sargassum fusiforme exhibiting anti-inflammatory responses in vitro and in vivo via modulation of TLR4/MyD88 and NF-κB signaling

Article Link

Year:

2024

Optimization, Metabolomic Analysis, Antioxidant Potential and Depigmenting Activity of Polyphenolic Compounds from Unmature Ajwa Date Seeds (Phoenix dactylifera L.) Using Ultrasonic-Assisted Extraction

Article Link

Year:

2024

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

Article Link

Year:

2023

Antioxidant, Tyrosinase, α-Glucosidase, and Elastase Enzyme Inhibition Activities of Optimized Unripe Ajwa Date Pulp (Phoenix dactylifera) Extracts by Response Surface Methodology

Article Link

Year:

2023

Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

Article Link

Year:

2023

Antibacterial Effect of Berberrubine on the Salmonella typhimurium Type III Secretion System

Article Link

Year:

2023

Identification and quantification of photodegradation products of disposed expanded polystyrene buoy used in aquaculture

Article Link

Year:

2023

Tyrosinase inhibitory activity of <scp>Sargassum fusiforme</scp> and characterisation of bioactive compounds

Article Link

Year:

2023

Metabolite profiling of Nymphaea rubra (Burm. f.) flower extracts using cyclic ion mobility–mass spectrometry and their associated biological activities

Article Link

Year:

2023

Metabolite Profiling of Microwave-Assisted Sargassum fusiforme Extracts with Improved Antioxidant Activity Using Hybrid Response Surface Methodology and Artificial Neural Networking-Genetic Algorithm

Article Link

Year:

2022

Anti-Influenza Virus Potential of Probiotic Strain Lactoplantibacillus plantarum YML015 Isolated from Korean Fermented Vegetable

Article Link

Year:

2022

Lariciresinol Displays Anti‐Diabetic Activity through Inhibition of α‐Glucosidase and Activation and Enhancement of Insulin Signaling

Article Link

Year:

2022

Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation of Oxidative Stress

Article Link

Year:

2022

Improved Image Analysis for Measuring Gastric Ulcer Index in Animal Models and Clinical Diagnostic Data

Article Link

Year:

2022

Fuzhuan Brick Tea Boosts Melanogenesis and Prevents Hair Graying through Reduction of Oxidative Stress via NRF2-HO-1 Signaling

Article Link

Year:

2022

Prunus mume Seed Exhibits Inhibitory Effect on Skin Senescence via SIRT1 and MMP-1 Regulation

Article Link

Year:

2021

Collaborators5

Sunghwan Kim

Kyungpook National University

SOUTH KOREA

Deokyeong Choe

Assistant Professor

Kyungpook National University

SOUTH KOREA

Sae-Byuk Lee

Kyungpook National University

SOUTH KOREA

MD BADRUL ALAM

Research Professor

Kyungpook National University

SOUTH KOREA

Rajib Majumder

University of Sydney

AUSTRALIA

How do I reach out?

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Sang-Han Lee

Professor, Director

How do I reach out?

Contact this professor

Research Interests

Ask ApplyKite AI

Recent Grants

Articles25

Comparative Metabolite Profiling of Antarctic and Korean Mosses: Insights into Adaptation Mechanisms of Antarctic Moss Species

In silico analysis of dual tyrosinase and elastase inhibition by bioactive ingredients from Gardenia jasminoides seeds

Physicochemical and sensory evaluation of additive-free hot-air dried applemango (Mangifera indica L. var. Irwin) fruit leathers

Research Progress on Anti-Aging with Natural Products: From Pathway Modulation to AI-Driven Discovery

Betulinic Acid-Enriched Dillenia indica L. Bark Extract Attenuates UVB-Induced Skin Aging via KEAP1-Mediated Antioxidant Pathways

γ-Mangosteen, an autophagy enhancer, prevents skin-aging via activating KEAP1/NRF2 signaling and downregulating MAPKs/AP-1/NF-κB-mediated MMPs

RSM- and ANN-Based Multifrequency Ultrasonic Extraction of Polyphenol-Rich Sargassum horneri Extracts Exerting Antioxidative Activity via the Regulation of MAPK/Nrf2/HO-1 Machinery

Biological activities, identification, method development, and validation for analysis of polyphenolic compounds in <i>Nymphaea rubra</i> flowers and leaves by UHPLC‐Q‐cIM‐TOF‐MS and UHPLC‐TQ‐MS

Development of a rapid screening method utilizing 2D LC for effect-directed analysis in the identification of environmental toxicants

Glycoprotein from Sargassum fusiforme exhibiting anti-inflammatory responses in vitro and in vivo via modulation of TLR4/MyD88 and NF-κB signaling

Optimization, Metabolomic Analysis, Antioxidant Potential and Depigmenting Activity of Polyphenolic Compounds from Unmature Ajwa Date Seeds (Phoenix dactylifera L.) Using Ultrasonic-Assisted Extraction

Profiling of Secondary Metabolites of Optimized Ripe Ajwa Date Pulp (Phoenix dactylifera L.) Using Response Surface Methodology and Artificial Neural Network

Antioxidant, Tyrosinase, α-Glucosidase, and Elastase Enzyme Inhibition Activities of Optimized Unripe Ajwa Date Pulp (Phoenix dactylifera) Extracts by Response Surface Methodology

Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

Antibacterial Effect of Berberrubine on the Salmonella typhimurium Type III Secretion System

Identification and quantification of photodegradation products of disposed expanded polystyrene buoy used in aquaculture

Tyrosinase inhibitory activity of <scp><i>Sargassum fusiforme</i></scp> and characterisation of bioactive compounds

Metabolite profiling of Nymphaea rubra (Burm. f.) flower extracts using cyclic ion mobility–mass spectrometry and their associated biological activities

Metabolite Profiling of Microwave-Assisted Sargassum fusiforme Extracts with Improved Antioxidant Activity Using Hybrid Response Surface Methodology and Artificial Neural Networking-Genetic Algorithm

Anti-Influenza Virus Potential of Probiotic Strain Lactoplantibacillus plantarum YML015 Isolated from Korean Fermented Vegetable

Lariciresinol Displays Anti‐Diabetic Activity through Inhibition of α‐Glucosidase and Activation and Enhancement of Insulin Signaling

Terpenoid-Rich Extract of Dillenia indica L. Bark Displays Antidiabetic Action in Insulin-Resistant C2C12 Cells and STZ-Induced Diabetic Mice by Attenuation of Oxidative Stress

Improved Image Analysis for Measuring Gastric Ulcer Index in Animal Models and Clinical Diagnostic Data

Fuzhuan Brick Tea Boosts Melanogenesis and Prevents Hair Graying through Reduction of Oxidative Stress via <i>NRF2</i>-<i>HO-1</i> Signaling

Prunus mume Seed Exhibits Inhibitory Effect on Skin Senescence via SIRT1 and MMP-1 Regulation

Collaborators5

Sunghwan Kim

Deokyeong Choe

Sae-Byuk Lee

MD BADRUL ALAM

Rajib Majumder

How do I reach out?