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Sarah Mundt

Has grant

Group leader Neuroimmunology

University Hospital of Zurich

Switzerland

Research Interests

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Professors in Switzerland Professors in Immunology Immunology professors in Switzerland

Recent Grants

Grant: Open

Niche-Imprinted Monocyte Programs as Therapeutic Targets in Progressive Multiple Sclerosis

Open Date: 2026-04-01

Close Date: 2027-03-01

Grant: Close

Disentangling pathogenic and protective features of CNS phagocytes – a dual role of MerTK in neuroinflammation?

Open Date: 2024-01-01

Close Date: 2025-12-01

Grant: Close

Spatiotemporal characterization of progression associated monocyte derived cells (paMdCs) in mouse and human neuroinflammation

Open Date: 2024-01-01

Close Date: 2025-01-01

Grant: Close

Profiling progression associated phagocytes in CNS autoimmunity

Open Date: 2024-01-01

Close Date: 2024-12-01

Grant: Close

CNS associated T cells: Studying their fate in tissue homeostasis versus autoimmunity

Open Date: 2023-01-01

Close Date: 2023-12-01

Articles (15)

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2026

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2023

Collaborators (20)

Juan Villar-Vesga

University of Zurich

SWITZERLAND

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Andreas J. Hülsmeier

University Hospital of Zurich

SWITZERLAND

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Annika Keller

University Hospital of Zurich

SWITZERLAND

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Isabelle C. Arnold

Assistant Professor

University of Zurich

SWITZERLAND

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Ari Molofsky

Associate Professor

University of California, San Francisco

UNITED STATES

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Manfred Kopf

Professor

ETH Zürich

SWITZERLAND

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Christoph Schneider

University of Zurich

SWITZERLAND

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Shiva Tyagarajan

Professor

University of Coimbra

PORTUGAL

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Frank Heppner

Director

Charité - Universitätsmedizin Berlin

GERMANY

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Nicholas S R Sanderson

SWITZERLAND

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Melanie Greter

University of Zurich

SWITZERLAND

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Mitchell Bijnen

University of Zurich

SWITZERLAND

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Basak Corak

University of Zurich

SWITZERLAND

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Hubert Rehrauer

SWITZERLAND

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Margherita Zamboni

Karolinska Institutet

SWEDEN

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Sinduya Krishnarajah

University of Zurich

SWITZERLAND

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Torben Ruhwedel

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Alexandar Tzankov

Head Histopathology and Autopsy

University Hospital Basel

SWITZERLAND

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Burkhard Becher

University of Zurich

SWITZERLAND

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Nicola Aceto

Professor of Molecular Oncology

ETH Zürich

SWITZERLAND

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Sarah Mundt

Research Interests

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Recent Grants

Articles (15)

Monocyte-derived macrophages drive neurological tissue damage through mitochondrial reactive oxygen species

Deletion of Lymphatic PD-L1 Protects Mice From Severe Autoimmune Encephalitis.

Multimodal transcriptomics reveal neurogenic aging trajectories and age-related regional inflammation in the dentate gyrus

PDL1-expressing macrophages infiltrate diffuse large B-cell lymphoma and promote lymphoma growth in a MYC-driven experimental model.

GM-CSF derived from alveolar type 2 cells promotes CD301b⁺ cDC2 generation and allergic airway inflammation

Interleukin-12 signaling drives Alzheimer’s disease pathology through disrupting neuronal and oligodendrocyte homeostasis

Interleukin-34-dependent perivascular macrophages promote vascular function in the brain.

Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology

B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis

Mononuclear phagocytes in autoimmune neuroinflammation

Twin study dissects CXCR3+ memory B cells as non-heritable feature in multiple sclerosis

The Significant Role of PA28αβ in CD8<sup>+</sup> T Cell-Mediated Graft Rejection Contrasts with Its Negligible Impact on the Generation of MHC-I Ligands.

Antibodies Produced by CLL Phenotype B Cells in Patients With Myasthenia Gravis Are Not Directed Against Neuromuscular Endplates

High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity

IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice.

Collaborators (20)

Juan Villar-Vesga

Andreas J. Hülsmeier

Annika Keller

Isabelle C. Arnold

Ari Molofsky

Manfred Kopf

Christoph Schneider

Shiva Tyagarajan

Frank Heppner

Nicholas S R Sanderson

Melanie Greter

Mitchell Bijnen

Basak Corak

Hubert Rehrauer

Margherita Zamboni

Sinduya Krishnarajah

Torben Ruhwedel

Alexandar Tzankov

Burkhard Becher

Nicola Aceto

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