Shane Wright

Karolinska Institutet

Sweden

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Articles (14)

Year:

2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (15)

Mette Marie Rosenkilde

Københavns Universitet

DENMARK

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Joris Hoeks

University of Maastricht

NETHERLANDS

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Stefania Koutsilieri

Karolinska Institutet

SWEDEN

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Peter Lindquist

Københavns Universitet

DENMARK

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Kimmie Vestergaard Sørensen

Københavns Universitet

DENMARK

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Christian Michel Beusch

Karolinska Institutet

SWEDEN

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Thor Møller

Københavns Universitet

DENMARK

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Volker Lauschke

Professor

Karolinska Institutet

SWEDEN

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Vanessa Monteil

Karolinska Institutet

SWEDEN

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Camilla Scheele

Københavns Universitet

DENMARK

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Carl-Fredrik Bowin

Københavns Universitet

DENMARK

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Bolette Hartmann

Københavns Universitet

DENMARK

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Signe Mathiasen

Assistant Professor

University of Copenhagen

DENMARK

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Lærke Smidt Gasbjerg

Københavns Universitet

DENMARK

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Josef M. Penninger

The University of British Columbia

CANADA

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Shane Wright

Research Interests

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Articles (14)

Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge

Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.

Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling

Rewiring of catecholamine‐induced calcium signalling is an early event in non‐alcoholic fatty liver disease

Rewiring of catecholamine‐induced calcium signalling is an early event in non‐alcoholic fatty liver disease

GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics

Illuminating the complexity of GPCR pathway selectivity – advances in biosensor development

Organotypic human ex vivo models for coronavirus disease 2019 research and drug development

Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes

Agonist-induced formation of unproductive receptor-G<sub>12</sub> complexes.

Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis

Collaborators (15)

Mette Marie Rosenkilde

Joris Hoeks

Stefania Koutsilieri

Peter Lindquist

Kimmie Vestergaard Sørensen

Christian Michel Beusch

Thor Møller

Volker Lauschke

Vanessa Monteil

Camilla Scheele

Carl-Fredrik Bowin

Bolette Hartmann

Signe Mathiasen

Lærke Smidt Gasbjerg

Josef M. Penninger

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