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Shyuan Ngo

Has grant

Director

University of Queensland

Australia

Research Interests

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Professors in Australia

Recent Grants

Grant: Open

MetFlex 2: A phase 2 trial to assess the efficacy of Trimetazidine modulation of metabolic flexibility in amyotrophic lateral sclerosis (ALS)

Open Date: 2026-09-01

Close Date: 2029-09-01

Grant: Open

Discovery of novel microglial targets for ALS using immuno-competent spinal organoids

Open Date: 2026-02-01

Close Date: 2029-02-01

Grant: Open

Preserving mobility in Motor Neurone Disease: Integrating high-resolution biomechanical analysis and robotic assistive devices to support movement in plwMND

Open Date: 2026-01-01

Close Date: 2028-01-01

Grant: Open

Tailoring Nutrition in MND: A co-designed study linking lipid profiles with dietary intake

Open Date: 2025-05-01

Close Date: 2027-05-01

Grant: Open

Using the spatiotemporal dynamics signature of molecular pathology to decipher disease heterogeneity in ALS

Open Date: 2025-02-01

Close Date: 2027-02-01

Articles (20)

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Collaborators (14)

Matthew C. Kiernan

University of Sydney

AUSTRALIA

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Markus Barth

Professor Biomedical Engineering

University of Queensland

AUSTRALIA

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Makoto Urushitani

Dean

Shiga University of Medical Science

JAPAN

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Harriet Dempsey-Jones

University of Queensland

AUSTRALIA

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Kelly Garner

Senior Lecturer

University of New South Wales

AUSTRALIA

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Ammar Al-Chalabi

Professor of Neurology and Complex Disease Genetics

King’s College London

UNITED KINGDOM

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Frederik Steyn

Associate Professor

University of Queensland

AUSTRALIA

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Mike Thompson

Professor Associat

Universitat Politècnica de Catalunya

SPAIN

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Anita Beelen

Senior researcher

University Medical Center Groningen

NETHERLANDS

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Christopher Lewis

Københavns Universitet

DENMARK

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Leonard Van den Berg

Universitair Medisch Centrum Utrecht

NETHERLANDS

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Taylor J. M. Dick

University of Queensland

AUSTRALIA

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Ryutaro Nakamura

Shiga University of Medical Science

JAPAN

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Julien Ochala

Associate Professor

Københavns Universitet

DENMARK

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Shyuan Ngo

Research Interests

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Recent Grants

Articles (20)

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Systemic immune-metabolic interactions in patients with amyotrophic lateral sclerosis: correlations of plasma cytokines with metabolic status

Review of the Pathology of Muscle in Amyotrophic Lateral Sclerosis

Segmentation of the human tongue musculature using MRI: Field guide and validation in motor neuron disease

An Annotated Multi-Site and Multi-Contrast Magnetic Resonance Imaging Dataset for the study of the Human Tongue Musculature

Persistent high levels of perceived fatigue are not associated with hypermetabolism in patients with amyotrophic lateral sclerosis

Site-specific quantification of the in vivo UFMylome reveals myosin modification in ALS

Examining the impact and role of lipid classes on the risk of amyotrophic lateral sclerosis (ALS) onset: a systematic review and GRADE analysis of the evidence.

Epigenetic profiles of tissue informative CpGs inform ALS disease status and progression.

Deciphering hypothalamic pathology in ALS: insights into non-motor symptoms and disease progression.

Lower-limb biomechanics in motor neuron disease: a joint-level perspective of gait disruption.

Assessment of the "MND-Prism" smartphone application as a tool for self-management.

Identification of passive wrist-worn accelerometry outcomes for improved disease monitoring and trial design in motor neuron disease.

An fMRI dataset for appetite neural correlates in people living with Motor Neuron Disease.

Appetite loss in patients with motor neuron disease: impact on weight loss and neural correlates of visual food cues.

Long-term fixation impact on archived human nervous tissues for sequencing-based transcriptomics

Variation in Resting Metabolic Rate Affects Identification of Metabolic Change in Geographically Distinct Cohorts of Patients With ALS

An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis

Generation of human induced pluripotent stem cell lines from sporadic, sporadic frontotemporal dementia, familial SOD1, and familial C9orf72 amyotrophic lateral sclerosis (ALS) patients

Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in amyotrophic lateral sclerosis

Collaborators (14)

Matthew C. Kiernan

Markus Barth

Makoto Urushitani

Harriet Dempsey-Jones

Kelly Garner

Ammar Al-Chalabi

Frederik Steyn

Mike Thompson

Anita Beelen

Christopher Lewis

Leonard Van den Berg

Taylor J. M. Dick

Ryutaro Nakamura

Julien Ochala

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