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Sibylle Grad

Has grant

Lecturer

ETH Zürich

Switzerland

Research Interests

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Professors in Switzerland Professors in Tissue Engineering Tissue Engineering professors in Switzerland

Recent Grants

Grant: Open

Under the skin: Unraveling the neuromodulatory role of skin cells in Complex Regional Pain Syndrome

Open Date: 2026-01-01

Close Date: 2029-12-31

Grant: Open

DISC-Overy Biofabricating the next generation of a whole intervertebral disc model

Open Date: 2026-01-01

Close Date: 2029-12-31

Grant: Open

Injectable spheroid-loaded microscaffolds for intervertebral disc repair

Open Date: 2023-08-01

Close Date: 2027-07-31

Grant: Close

Tissue engineering-inspired, regenerative approaches for OA-tuned mechanotherapy

Open Date: 2023-08-01

Close Date: 2024-07-31

Grant: Close

eCMXXI Conference: Cartilage and Disc - Repair and Regeneration

Open Date: 2022-05-01

Close Date: 2022-07-31

Articles (27)

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Collaborators (29)

Cornelia Neidlinger-Wilke

Universität Ulm

GERMANY

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Oliver Distler

University Hospital of Zurich

SWITZERLAND

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Julia Fernández-Pérez

TU Wien

AUSTRIA

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Jess G. Snedeker

Full Professor

Balgrist University Hospital

SWITZERLAND

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Zhen Li

Principal Scientist

AO Research Institute Davos

SWITZERLAND

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Gaia Rocchitta

Ricercatore confermato

University of Sassari

ITALY

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Laura Creemers

Associate professor

University of Maastricht

NETHERLANDS

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Graciosa Q. Teixeira

Principal Investigator

Ulm University

GERMANY

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Francis Berenbaum

Assistance Publique - Hôpitaux de Paris

FRANCE

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Ilse Jonkers

Katholieke Universiteit Leuven

BELGIUM

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Stefan Dudli

University of Zurich

SWITZERLAND

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Elias Salzer

Eindhoven University of Technology

NETHERLANDS

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Aleksandr Ovsianikov

Professor

TU Wien

AUSTRIA

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Marcin Waligora

Chair/Associate Professor

Jagiellonian University Medical College

POLAND

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mehdi khanmohammadi

Assistant professor

University of Sheffield

UNITED KINGDOM

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Tiziano Serra

Assistant Professor

NETHERLANDS

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Chunyi Wen

The Hong Kong Polytechnic University

HONG KONG

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Hans‐Joachim Wilke

Ulm University

GERMANY

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Valentina Basoli

Group Leader Biofabrication and Biosensor Unit

University of Basel

SWITZERLAND

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Mauro Alini

AO Research Institute Davos

SWITZERLAND

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Martin Stoddart

AO Research Institute Davos

SWITZERLAND

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Andrea Vernengo

Associate Professor

Rowan University

UNITED STATES

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Matteo D'Este

AO Research Institute Davos

SWITZERLAND

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Gianluca Vadalà

Associate Professor

Università Campus Bio-Medico di Roma

ITALY

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Stipe Ćorluka

CROATIA

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Jacek Wychowaniec

Senior Research Scientist; incoming Associate Professor in Medical Biotechnology

University of Southern Denmark

DENMARK

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Luca Ambrosio

Orthopaedic Surgeon

Campus Bio Medico University Hospital

ITALY

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Christoph Albers

University Hospital of Bern

SWITZERLAND

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Sonja Häckel

University of Bern

SWITZERLAND

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Sibylle Grad

Research Interests

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Recent Grants

Articles (27)

A multifactorial intervertebral disc degeneration model: Integrating inflammation, structural disruption, biomechanical parameters, and neural sensitization

Exploring Injectable Scaffolded Spheroids for Nucleus Pulposus Therapy in Degenerated Intervertebral Discs

Anti-inflammatory and anabolic effects of liraglutide on 3D inflammatory osteoarthritic spheroid and scaffold models of human chondrocytes

Single-Step Extrusion Printing of Microgrooved Annulus Fibrosus Scaffolds via Patterned Nozzles

YAP1 Knockdown Reduces IL-1β-Induced Human Chondrocyte Inflammation and Promotes Human MSC Chondrogenesis

Mechanistic insights into cartilage-sensory nerve crosstalk in osteoarthritis progression

Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs

Crosslinking strategies govern the morphology and biological performance of decellularized extracellular matrix particle–tyramine-modified hyaluronic acid hydrogels

Bracing and Activity Restriction After Lumbar Discectomy Surgery: An International Survey of AO Spine Members

Combined Flexion, Torsion and Compression Drive Distinct Intervertebral Disc Failure Mechanisms Under Asymmetric, High‐Cycle Loading

Emerging Circulating Molecular Biomarkers: New Horizons in Lumbar Disc Herniation

Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc

Biological Sex Is Under‐Reported in Cartilage‐Related Preclinical Research: A Cross‐Sectional Analysis

Optimized hydrogel viscoelasticity and interlocking patch repair enhance compressive range of motion in injured discs and prevent re-herniation under physiological load in an Ex Vivo model

Real-time nitric oxide and inflammation sensing in 2D osteoarthritis models: microsensor design and application

Short‐Term Dynamic Unloading of Bovine Tail Discs in Culture Partially Mitigates Induced Degeneration After One‐Strike Trigger

Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors

Papain Injection Creates a Nucleotomy-like Cavity for Testing Gels in Intervertebral Discs

Proteomic analysis of serum in a population‐based cohort did not reveal a biomarker for Modic changes

Cartilage tissue engineering using decellularized biomatrix hydrogel containing TGF-β-loaded alginate microspheres in mechanically loaded bioreactor

ESTABLISHMENT OF A COCULTURE SYSTEM WITH OSTEOCHONDRAL AND SYNOVIAL EXPLANTS AS AN EX VIVO INFLAMMATORY OSTEOARTHRITIS MODEL

Engineering Sensory Ganglion Multicellular System to Model Tissue Nerve Ingrowth

NOGGIN INHIBITS TGF-β1 OR TGF-β3 INDUCED CHONDROGENESIS OF MESENCHYMAL STROMAL CELLS

Response of Articular Cartilage to Hyperosmolar Stress: Report of an Ex Vivo Injury Model

Anti-inflammatory and anabolic biphasic scaffold facilitates osteochondral tissue regeneration in osteoarthritic joints

Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models

A Novel Fiber-Reinforced Poroviscoelastic Bovine Intervertebral Disc Finite Element Model for Organ Culture Experiment Simulations

Collaborators (29)

Cornelia Neidlinger-Wilke

Oliver Distler

Julia Fernández-Pérez

Jess G. Snedeker

Zhen Li

Gaia Rocchitta

Laura Creemers

Graciosa Q. Teixeira

Francis Berenbaum

Ilse Jonkers

Stefan Dudli

Elias Salzer

Aleksandr Ovsianikov

Marcin Waligora

mehdi khanmohammadi

Tiziano Serra

Chunyi Wen

Hans‐Joachim Wilke

Valentina Basoli

Mauro Alini

Martin Stoddart

Andrea Vernengo

Matteo D'Este

Gianluca Vadalà

Stipe Ćorluka

Jacek Wychowaniec

Luca Ambrosio

Christoph Albers

Sonja Häckel

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