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Zhen Li

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Principal Scientist

AO Research Institute Davos

Switzerland

Research Interests

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Professors in Switzerland Professors in Tissue Engineering Tissue Engineering professors in Switzerland

Recent Grants

Grant: Close

EORS-Aesculap Award

Open Date: 2025-06-01

Close Date:

Grant: Close

NetwOArk: Building an open European Network on OsteoArthritis research

Open Date: 2022-10-01

Close Date: 2026-10-01

Grant: Close

SinPain: A game changer for the treatment of osteoarthritis: a cost effective combined advanced therapy to treat knee osteoarthritis

Open Date: 2022-05-01

Close Date: 2026-10-01

Grant: Close

OA_BIO: Life changing therapy for Osteo-Arthritis patients: a biomarker lead approach

Open Date: 2021-05-01

Close Date: 2024-10-01

Grant: Close

Neoepitope peptides as biomarkers of early intervertebral disc degeneration

Open Date: 2020-11-01

Close Date: 2021-11-01

Articles (20)

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Collaborators (15)

Yangzi Jiang

University of Pittsburgh

UNITED STATES

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Francis Berenbaum

Assistance Publique - Hôpitaux de Paris

FRANCE

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Carsten Riether

University Hospital of Bern

SWITZERLAND

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Chunyi Wen

The Hong Kong Polytechnic University

HONG KONG

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Fatemeh Safari

University of Bern

SWITZERLAND

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Marie-Astrid Boutet

Chargée de Recherche de Classe Normale (CRCN)

INSERM

FRANCE

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Mauro Alini

AO Research Institute Davos

SWITZERLAND

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Martin Stoddart

AO Research Institute Davos

SWITZERLAND

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Qing Jun Meng

The University of Manchester

UNITED KINGDOM

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Sibylle Grad

Lecturer

ETH Zürich

SWITZERLAND

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Matteo D'Este

AO Research Institute Davos

SWITZERLAND

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Jacek Wychowaniec

Senior Research Scientist; incoming Associate Professor in Medical Biotechnology

University of Southern Denmark

DENMARK

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Christoph Albers

University Hospital of Bern

SWITZERLAND

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Girish Pattappa

Senior Scientist

University of Würzburg

GERMANY

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Sonja Häckel

University of Bern

SWITZERLAND

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Zhen Li

Research Interests

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Recent Grants

Articles (20)

Anti-inflammatory and anabolic effects of liraglutide on 3D inflammatory osteoarthritic spheroid and scaffold models of human chondrocytes

Mechanistic insights into cartilage-sensory nerve crosstalk in osteoarthritis progression

Single-Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Crosslinking strategies govern the morphology and biological performance of decellularized extracellular matrix particle–tyramine-modified hyaluronic acid hydrogels

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Synergistic organic–inorganic assembly enhances condylar osteochondral interface mechanics

Novel therapeutic strategies for osteoarthritis: from mechanistic insights to precision medicine

A Quantitative visualized review on clinically informed temporomandibular joint animal models

Region-dependent expression and function of integrin α5β1 in protecting against disc degeneration via autophagy promotion: an ex vivo organ culture model under dynamic mechanical loading

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc

Application of tissue engineering approaches in osteoarthritis

Towards stratification in osteoarthritis: a review of the scientific terminology used in published basic research.

Noggin expression in human nucleus pulposus cells: A comparative study of degenerative and traumatic intervertebral discs

Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly

ATG7-driven mitophagy in BMSC@CS hydrogel reprograms metabolism to boost bone regeneration

Bio-catalytic preparation of poly(methacrylic acid) hydrogels using peroxidase from potato peel waste and preliminary evaluation of their anti-inflammatory potential

Phytomolecule Epimedin C Mitigates Cartilage Extracellular Matrix Degradation and Osteoarthritis Progression in Rats

The Role of the Bone Morphogenetic Protein Antagonist Noggin in Nucleus Pulposus Intervertebral Disc Cells

Decellularized extracellular matrix-based hydrogels for cartilage repair and regeneration

Collaborators (15)

Yangzi Jiang

Francis Berenbaum

Carsten Riether

Chunyi Wen

Fatemeh Safari

Marie-Astrid Boutet

Mauro Alini

Martin Stoddart

Qing Jun Meng

Sibylle Grad

Matteo D'Este

Jacek Wychowaniec

Christoph Albers

Girish Pattappa

Sonja Häckel

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