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Sjors Scheres

Group Leader

MRC Laboratory of Molecular Biology

United Kingdom

Research Interests

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Articles (14)

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2026

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2026

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2025

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2025

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2023

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2023

Collaborators (8)

David Barford

Joint Head of Division

MRC Laboratory of Molecular Biology

UNITED KINGDOM

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Max Wilkinson

Assistant Member

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Taxiarchis Katsinelos

Assistant Professor

Aristotle University of Thessaloniki

GREECE

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Michele Vendruscolo

Professor

University of Cambridge

UNITED KINGDOM

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Johannes Schwab

University of Applied Sciences Kufstein

AUSTRIA

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Jacob McPhail

Professional Researcher

University of California, San Francisco

UNITED STATES

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Alan Brown

Professor

Harvard Medical School

UNITED STATES

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Lukas Käll

KTH Royal Institute of Technology

SWEDEN

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Sjors Scheres

Research Interests

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Articles (14)

The amyloid packing difference: A pairwise comparison metric for amyloid structures

Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

Seeding biosensor cell line that reproduces the Alzheimer tau fold

GSK3β phosphorylated tau filaments are probably not like those from AD brains

Automated model building and protein identification in cryo-EM maps

DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images

Data-driven regularization lowers the size barrier of cryo-EM structure determination

An image processing pipeline for electron cryo‐tomography in RELION‐5

Alzheimer’s plaques and tangles revealed by 3D microscopy

Disease-specific tau filaments assemble via polymorphic intermediates

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.

Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids

Collaborators (8)

David Barford

Max Wilkinson

Taxiarchis Katsinelos

Michele Vendruscolo

Johannes Schwab

Jacob McPhail

Alan Brown

Lukas Käll

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