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Stan Hazen

Has grant

Director, Center for Microbiome and Human Health

Cleveland Clinic

United States

Research Interests

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Recent Grants

Grant: Open

Artificial sweeteners and cardiovascular disease

Open Date: 2025-03-04

Close Date: 2028-12-31

Grant: Open

Nutrition, terminal NAD metabolites and cardiovascular disease

Open Date: 2024-06-01

Close Date: 2028-04-30

Grant: Open

Gut microbial dietary phenylalanine metabolism and heart failure

Open Date: 2024-01-05

Close Date: 2027-12-31

Grant: Close

Gut Microbiota and Cardiometabolic Diseases

Open Date: 2019-09-01

Close Date: 2025-07-31

Grant: Close

Microbiota-metabolic effects on the vascular thrombogenicity and inflammation

Open Date: 2018-01-01

Close Date: 2022-12-31

Articles (20)

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Collaborators (21)

Arjun Deb

Professor/Director

University of California, Los Angeles

UNITED STATES

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Dylan Dodd

Assistant Professor

Stanford University

UNITED STATES

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Sarah Best

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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David Nanchen

Associate Professor

University of Lausanne

SWITZERLAND

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Defne Bayik

Assistant Professor

Sylvester Comprehensive Cancer Center

UNITED STATES

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Annabel Biruete

Assistant Professor

Purdue University

UNITED STATES

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Matthew Budoff

The Lundquist Institute

UNITED STATES

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Matthew Grabowski

Staff

Cleveland Clinic

UNITED STATES

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Jakob Steinfeldt

Charité - Universitätsmedizin Berlin

GERMANY

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Rozenn Lemaitre

University of Washington

UNITED STATES

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Howard Hu

Chair and Professor (2020-2024; on sabbatical 2024-2025)

University of Southern California Keck School of Medicine

UNITED STATES

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Florian A. Wenzl

University of Zurich

SWITZERLAND

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Frank Gilliland

Prof

University of Southern California

UNITED STATES

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Christian Weber

Chair in Vascular Medicine and Physician-in-Chief

LMU Klinikum

GERMANY

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Fredrik Bäckhed

Professor

University of Gothenburg

SWEDEN

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aldons lusis

prof

David Geffen School of Medicine at UCLA

UNITED STATES

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Maximilian König

University Medicine Greifswald

GERMANY

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Sarah Costantino

Phd, Group leader

University Hospital of Zurich

SWITZERLAND

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Nicolle Kraenkel

Charité - Universitätsmedizin Berlin

GERMANY

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Erik Hoon Van Iterson

Director, Cardiopulmonary Exercise Testing CORE Laboratory

Cleveland Clinic

UNITED STATES

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Kristina Penniston

Distinguished Senior Scientist

University of Wisconsin-Madison

UNITED STATES

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Stan Hazen

Research Interests

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Recent Grants

Articles (20)

Lipid‐Lowering Effects of Inclisiran in Statin‐ or PCSK9i Monoclonal Antibody‐Intolerant Individuals

Plasma indole-3-propionic acid is a gut-derived metabolite and is associated with type 2 diabetes and cardiometabolic outcomes: Evidence from a human antibiotic intervention

Gut microbiota-derived imidazole propionate predicts cardiometabolic risk in patients with coronary artery disease

Exploring the Role of Glycine Metabolism in Coronary Artery Disease: Insights from Human Genetics and Mouse Models

Associations of Plasma Trimethylamine N-Oxide-Related Metabolites with the Development and Progression of Albuminuria: The Multi-Ethnic Study of Atherosclerosis

Gut Microbial Metabolite Imidazole Propionate Impairs Endothelial Cell Function and Promotes the Development of Atherosclerosis

Microbiota and kidney disease: the road ahead.

NAD&lt;sup&gt;+&lt;/sup&gt; boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice.

Circulating Trimethylamine <i>N</i>-Oxide and Growth Rate of Abdominal Aortic Aneurysms and Surgical Risk

Trimethylamine-N-Oxide Affects Cell Type–Specific Pathways and Networks in Mouse Aorta to Promote Atherosclerotic Plaque Vulnerability

Erythritol and xylitol and cardiovascular disease risk: a growing concern

Xylitol and cardiovascular risks

Microbiome–metabolome dynamics associated with impaired glucose control and responses to lifestyle changes

Leveraging Dysregulated Tumor Metabolism for targeting anti-cancer bacteria

Abbreviated Duke Activity Status Index for Risk Stratification in Heart Failure

Development of non-lethal mechanism-based small molecule inhibitors of the gut microbial phenylacetylglutamine pathway in cardiovascular disease

Trimethylamine-<i>N</i>-oxide (TMAO) and risk of incident cardiovascular events in the multi ethnic study of Atherosclerosis

COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type

Tumor cell-derived spermidine promotes a protumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.

Alcohol-induced gut microbial reorganization and associated overproduction of phenylacetylglutamine promotes cardiovascular disease.

Collaborators (21)

Arjun Deb

Dylan Dodd

Sarah Best

David Nanchen

Defne Bayik

Annabel Biruete

Matthew Budoff

Matthew Grabowski

Jakob Steinfeldt

Rozenn Lemaitre

Howard Hu

Florian A. Wenzl

Frank Gilliland

Christian Weber

Fredrik Bäckhed

aldons lusis

Maximilian König

Sarah Costantino

Nicolle Kraenkel

Erik Hoon Van Iterson

Kristina Penniston

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NAD<sup>+</sup> boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice.