Stefania Angela Piccioni

Università degli Studi di Siena

Italy

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Articles (14)

Year:

2025

Year:

2025

Super-extended (D2plus) lymphadenectomy after chemotherapy has been reported in only a few studies. This retrospective study evaluates survival outcomes in a Western cohort of locally advanced or oligometastatic gastric cancer patients who underwent D2plus lymphadenectomy after neoadjuvant chemotherapy. A total of 97 patients treated between 2010 and 2022 were included. Of these, 62 had clinical stage II/III disease, and 35 had stage IV disease. Most patients (65%) received preoperative DOC/FLOT chemotherapy. The mean number of lymph nodes harvested was 39. Pathological positive nodes in the posterior/para-aortic stations occurred in 17 (17.5%) patients. Lymphovascular invasion, ypN stage, clinical stage, and perineural invasion were predictive factors for positive posterior/para-aortic nodes. Postoperative complications occurred in 21 patients, whereas severe complications (grade III or more) occurred in 9 cases (9.3%). Mortality rate was 1%. Median overall survival (OS) was 59 months (95% CI: 13–106), with a five-year survival rate of 49 ± 6%; the five-year OS after R0 surgery was 60 ± 7%. In patients with positive posterior/para-aortic nodes, the median OS was 15 months (95% CI: 13–18). D2plus lymphadenectomy after chemotherapy for locally advanced or oligometastatic gastric cancer is feasible and associated with low morbidity/mortality rates. The incidence of pathological metastases in posterior/para-aortic nodes is not negligible even after systemic chemotherapy, with poor long-term survival.

Year:

2024

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2023

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2023

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2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Collaborators (123)

Marian Vanhoeij

Vrije Universiteit Brussel

BELGIUM

Stefania Angela Piccioni

Research Interests

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Articles (14)

Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Malignancies with Palliative and Bidirectional Intent

Perforated Calculous Cholecystitis and Incidental Squamous Cell Carcinoma of the Gallbladder—A Complex Relationship with a Difficult Management in the Acute Setting

Posterior and Para-Aortic (D2plus) Lymphadenectomy after Neoadjuvant/Conversion Therapy for Locally Advanced/Oligometastatic Gastric Cancer

Extended Lymphadenectomy for Gastric Cancer in the Neoadjuvant Era: Current Status, Clinical Implications and Contentious Issues

Letter to the Editor: Kidney Transplantation and Obesity are There Any Differences in Outcomes?

Letter to the Editor: Kidney Transplantation and Obesity are There Any Differences in Outcomes?

Immunohistochemical Markers of the Epithelial-to-Mesenchymal Transition (EMT) Are Related to Extensive Lymph Nodal Spread, Peritoneal Dissemination, and Poor Prognosis in the Microsatellite-Stable Diffuse Histotype of Gastric Cancer

Immunohistochemical Markers of the Epithelial-to-Mesenchymal Transition (EMT) Are Related to Extensive Lymph Nodal Spread, Peritoneal Dissemination, and Poor Prognosis in the Microsatellite-Stable Diffuse Histotype of Gastric Cancer

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

Some Concerns from a Radiological Point of View. Comment on Huang et al. Outcomes of Conversion Surgery for Metastatic Gastric Cancer Compared with In-Front Surgery Plus Palliative Chemotherapy or In-Front Surgery Alone. J. Pers. Med. 2022, 12, 555

Some Concerns from a Radiological Point of View. Comment on Huang et al. Outcomes of Conversion Surgery for Metastatic Gastric Cancer Compared with In-Front Surgery Plus Palliative Chemotherapy or In-Front Surgery Alone. J. Pers. Med. 2022, 12, 555

SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

Collaborators (123)

Marian Vanhoeij

Satoshi Toyama

HERMAN SEHMBI

IOANNIS VALIOULIS

Jacobo Trebol

Ladislao Cayetano Paniagua

Chikashi Takeda

Matteo Marro

Daniel Perez

Paola Calleja Hermosa

Paul Nankivell

Laura Sala

Marion Delpont

Pierpaolo Sileri

BALTASAR PÉREZ-SABORIDO

Ruth Christine Schäfer

Saam Tourani

Ahmed Elshabrawy

Nolan Bruce

Daniel Jacobs-Tulleneers-Thevissen

Jiali Gao

Ulrich Ronellenfitsch

Paola Zinser Peniche

Marisa Domingues Santos

Jasper Stijns

Alastair Morton

Fanourios Georgiades

Nicholas Alexakis

Aina Brunet

Ruth A Benson

Francesco Doglietto

Richard McGee

Felix Naegele

Shafaque Shaikh

Lucy Huppler

Eiki Kanemaru

Manon Vounckx

Emma Howie

NICCOLO' DADDI

Chang Woo Kim

Florestan J. Koll

Amanda Caroline Dawson

Stephanie Hage

Adam Frankel

David C. Y. Tang

Allison Brown

Susana Gonzalez Suarez

Aimal Khan

Rhea Darbari Kaul

Kristin Colling

Emmanuel Katsogridakis

Shirley Jansen

Franco Roviello

Hilal A Al Sabti

Jeremy Wales

Luigi Marano

Luigi Rolli

Shomik Sengupta

Ishan Radotra

Amit Agrawal