Teresa Pinho e Melo

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Associate Professor with Habilitation

University of Coimbra

Portugal

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About

Teresa Pinho e Melo is an Associate Professor with Habilitation at the University of Coimbra, Portugal. Her research areas include the development of novel photosensitizers for photodynamic therapy in lung cancer, synthesis of chiral compounds, and exploring reactive intermediates in organic reactions. Recent publications highlight advancements in neuroprotective agents and the structural characterization of Schiff base complexes.

Recent Grants

Grant: Close

RESFINAS - Modificação de resinas de colofónia para promover a compatibilidade dos seus derivados com poliolefinas produzidas por catálise com metalocenos (PI at UC: Teresa Pinho e Melo)

Open Date: 2022-11-01

Close Date: 2025-10-01

Grant: Close

ResetFinas – Set up para modificação de resinas de colofónia para promover a compatibilidade dos seus derivados com poliolefinas produzidas com catálise com metalocenos (PI at UC: Teresa Pinho e Melo)

Open Date: 2022-11-01

Close Date: 2025-10-01

Grant: Close

TheraBullet – Complexos de Pt(II) derivados duma nova classe de clorinas: Validação de agentes de teranóstico do cancro (PI: Teresa Pinho e Melo)

Open Date: 2022-07-01

Close Date: 2023-06-01

Grant: Close

Chem4LungCare - Novel PolyPyrrole Scaffolds for Therapy and Imaging of Lung Cancer (PI: Teresa Pinho e Melo)

Open Date: 2022-01-01

Close Date: 2024-12-01

Grant: Close

MATIS - Sustainable Industrial Materials and Technologies

Open Date: 2017-01-01

Close Date: 2020-12-01

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Collaborators (19)

Marta Pineiro

Professor Auxiliar

University of Coimbra

PORTUGAL

Teresa Pinho e Melo

Research Interests

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About

Recent Grants

Articles (24)

trans-A2B-Corroles containing an oxime moiety: Novel photosensitizers for photodynamic therapy of lung cancer

Synthesis of Chiral Spirocyclopropanepenicillanates via [2 + 1] Annulation of 6-Alkylidenepenicillanates and Sulfur Ylides

Novel tetradentate N2O2 water-soluble Schiff Base and its Al(III) complex: Synthesis, structural characterization, and correlations between structure and stability against hydrolysis

Sulfur dioxide extrusion: Exploring the mechanism behind the formation of highly reactive 5-(trifluoromethyl)azafulvenium methide intermediates

Selective Synthesis of 3-(1H-Tetrazol-5-yl)-indoles from 2H-Azirines and Arynes

Unveiling the Red and Brownish-Green Polymorphs of a Novel ROY Derivative: 2-(4-((3-Cyanothiophen-2-yl)amino)-3-nitrophenyl)Acetic Acid

Chiral hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: the search for selective p53-activating agents for colorectal cancer therapy

On the mechanochemical synthesis of C-scorpionates with an oxime moiety and their application in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction

Hydrazone-Functionalized trans-A2B-Corroles: Effective Synergy in Photodynamic Therapy of Lung Cancer

P53 and the Ultraviolet Radiation-Induced Skin Response: Finding the Light in the Darkness of Triggered Carcinogenesis

Continuous Flow Spirocyclization Reactions: Towards Efficient Synthesis of Chiral Spiropenicillanates

Front Cover: Continuous Flow Spirocyclization Reactions: Towards Efficient Synthesis of Chiral Spiropenicillanates (Eur. J. Org. Chem. 42/2024)

3-Tetrazolyl-ß-carboline derivatives as potential neuroprotective agents

Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages

Ring-fused 3β-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties

The role of solvents and concentrations in the properties of oxime bearing A2B corroles

The role of solvents and concentrations in the properties of oxime bearing A<sub>2</sub>B corroles

Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts

Color Polymorphs of ROY-ol

High Instantaneous Inhibitory Potential of Bictegravir and the New Spiro-β-Lactam BSS-730A for HIV-2 Isolates from RAL-Naïve and RAL-Failing Patients

3-(1,2,3-Triazol-4-yl)-β-Carbolines and 3-(1H-Tetrazol-5-yl)-β-Carbolines: Synthesis and Evaluation as Anticancer Agents

Differential Tunneling-Driven and Vibrationally-Induced Reactivity in Isomeric Benzazirines

Applications of Photodynamic Therapy in Endometrial Diseases

Diels–Alder Cycloaddition Reactions in Sustainable Media

Collaborators (19)

Marta Pineiro

Isabel Barahona

Inês Bártolo

Sergio Seixas de Melo

M. Ermelinda Eusébio

Americo Lemos

ines Moura

Maria Filomena Botelho

Inês Ferreira

Cláudio M. Nunes

Maria Teresa Duarte

Luisa Martins

Otilia Vieira

José António Paixão

Nelson Pereira

Maria Soares

Mafalda Laranjo

Gisela Machado de Oliveira

Lucília Saraiva

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