Maria Soares

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Invited Assistant Professor

University of Coimbra

Portugal

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About

Maria Soares is an Invited Assistant Professor at the University of Coimbra, Portugal. Her research focuses on the mechanisms of reactive chemical intermediates, the role of glucosylated cholesterol in cardiovascular disease, and the synthesis of new compounds for therapeutic applications. Recent articles highlight her contributions to understanding lysosome dysfunction in macrophages and vascular smooth muscle cells, as well as the development of selective agents for cancer therapy.

Recent Grants

Grant: Close

Instituto de Ciências Moleculares

Open Date: 2021-01-01

Close Date: 2025-12-31

Grant: Close

Not Available

Open Date: 2019-01-02

Close Date: 2025-01-01

Grant: Close

Centro de Química - Coimbra

Open Date: 2019-01-01

Close Date: 2019-12-31

Grant: Close

Chemistry Triggered by Infrared Vibrational Excitation: Developing a Powerful Tool for Highly-Selective Molecular Structure Manipulation

Open Date: 2018-07-01

Close Date: 2022-07-01

Grant: Close

aCTIVE - Chemistry Triggered by Infrared Vibrational Excitation: Developing a Powerful Tool for Highly-Selective Molecular Structure Manipulation

Open Date: 2018-07-01

Close Date: 2022-07-01

Articles (10)

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2025

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2025

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2021

Collaborators (15)

Maria de Guadalupe Cabral

Universidade de Aveiro

PORTUGAL

Maria Soares

Research Interests

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About

Recent Grants

Articles (10)

Novel tetradentate N2O2 water-soluble Schiff Base and its Al(III) complex: Synthesis, structural characterization, and correlations between structure and stability against hydrolysis

Sulfur dioxide extrusion: Exploring the mechanism behind the formation of highly reactive 5-(trifluoromethyl)azafulvenium methide intermediates

Glucosylated cholesterol accumulates in atherosclerotic lesions and impacts macrophage immune response

Chiral hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: the search for selective p53-activating agents for colorectal cancer therapy

Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages

Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.

Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts

Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis

Diels–Alder Cycloaddition Reactions in Sustainable Media

Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium

Collaborators (15)

Maria de Guadalupe Cabral

Jorge Ferreira

Nuno Santos

Clare Futter

Inês Bártolo

Inês Ferreira

Teresa Pinho e Melo

Filomena Carvalho

Otilia Vieira

Antonio Jacinto

Marta Artola

Quélia Ribeiro

Gisela Machado de Oliveira

Lucília Saraiva

Michal Surma

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