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Tiinamaija Tuomi

Professor

University of Helsinki

Finland

Research Interests

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Professors in Finland Professors in Biostatistics Biostatistics professors in Finland

About

Dr. Tiinamaija Tuomi is an Associate Professor at the University of Helsinki, Finland. Her research primarily focuses on the genetic and environmental determinants of diabetes, including monogenic and autoimmune forms of the disease. She has published extensively on topics such as polygenic scores in type 2 diabetes, the impacts of fetal programming, and the interplay between autoimmune diseases and diabetes risk. Her work aims to enhance understanding and treatment strategies for diabetes and related cardiovascular complications.

Articles (46)

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Collaborators (115)

Hanna Ollila

University of Helsinki

FINLAND

Tiinamaija Tuomi

Research Interests

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About

Articles (46)

Lifestyle and environmental risk factors for adult-onset autoimmune diabetes: current evidence and future directions

Subgroups of Adult-Onset Diabetes

Metabolic Trajectories Before Diabetes Diagnosis Across Subgroups

Multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycaemic traits during pregnancy reveals limited evidence of pregnancy-specific genetic effects

Comprehensive genetic rescreening improves diagnostic yield in congenital hyperinsulinism

Genetic architecture of lumbar spinal stenosis

Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation

Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk

Pancreatic steatosis is a risk factor for pancreatic cysts among patients with diabetes

Comorbidities and mortality in subgroups of adults with diabetes with up to 14 years follow-up

Adult-onset type 1 diabetes: predictors of major cardiovascular events and mortality

Autoimmune diseases and the risk and prognosis of latent autoimmune diabetes in adults

Polygenic prediction of body mass index and obesity through the life course and across ancestries

Effects of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms

Exposure to antibiotics and risk of latent autoimmune diabetes in adults and type 2 diabetes: results from a Swedish case–control study (ESTRID) and the Norwegian HUNT study

Polygenic determinants of monogenic diabetes

Clinical use of polygenic scores in type 2 diabetes: challenges and possibilities

Fetal programming of early-onset type 2 diabetes

Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Alcohol consumption, genetic susceptibility, and risk of latent autoimmune diabetes in adults and type 2 diabetes

Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain

Selected miRNAs in Urinary Extracellular Vesicles Show Promise for Early and Specific Diagnostics of Diabetic Kidney Disease

Large-scale genome-wide analyses with proteomics integration reveal novel loci and biological insights into frailty

RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Metabolic profiling of smoking, associations with type 2 diabetes and interaction with genetic susceptibility

The hidden epidemic

International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes

A genomic mutational constraint map using variation in 76,156 human genomes

Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis

Inferring compound heterozygosity from large-scale exome sequencing data

Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review

Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis.

Genotype-stratified treatment for monogenic insulin resistance

Precision prognostics for cardiovascular disease in Type 2 diabetes

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Genetic analyses implicate complex links between adult testosterone levels and health and disease

Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases

Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease

Incidence of LADA and Type 2 Diabetes in Relation to Tobacco Use and Genetic Susceptibility to Type 2 Diabetes and Related Traits: Findings From a Swedish Case-Control Study and the Norwegian HUNT Study

Identification of monogenic variants in more than ten per cent of children without type 1 diabetes-related autoantibodies at diagnosis in the Finnish Pediatric Diabetes Register

Capturing the Kidney Transcriptome by Urinary Extracellular Vesicles-From Pre-Analytical Obstacles to Biomarker Research

Residual insulin secretion in individuals with type 1 diabetes in Finland: longitudinal and cross-sectional analyses

Antioxidant Nutrients and Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes: A Swedish Case-Control Study and Mendelian Randomization Analysis

An insulin hypersecretion phenotype precedes pancreatic β cell failure in MODY3 patient-specific cells

Does a prior diagnosis of infectious disease confer an increased risk of latent autoimmune diabetes in adults?

Collaborators (115)

Hanna Ollila

Mara Parellada

Joel Rämö

Paula Kauppi

Andrea Ganna

Timo Sipilä

Laura Rasmussen-Torvik

David Mackey AO

Matti Pirinen

Joel Hirschhorn

Dennis Mook-Kanamori

Lars Ängquist

Tasanee Braithwaite

Paula Vähäsalo

Struan Grant

Mark Pereira

Nicholas Timpson

Maija Puhka

Jarno Kettunen

sofia carlsson

Julia Zollner

Matthieu Allez

Diego Balboa

Sebastian Barg

Dirk Paul

Riitta Veijola

Jordi Merino

Aude Deydier