Tom Houben

Assistant Professor

Netherlands

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Tom Houben is an Assistant Professor at Maastricht University, NUTRIM in the Netherlands. His research areas focus on metabolic dysfunctions, liver disease indicators, and the role of lipids in major depressive disorder. Recent publications include studies on cathepsin D's impact on liver lipidome and its association with alcohol-related liver disease, as well as investigations into the implications of metabolic shifts in cancer cells.

Articles (18)

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2024

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (4)

Klary E. Niezen-Koning

University Medical Center Groningen

NETHERLANDS

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Dennis Meesters

University of Maastricht

NETHERLANDS

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Ronit Shiri-Sverdlov

University of Maastricht

NETHERLANDS

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Jan Theys

University of Maastricht

NETHERLANDS

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Tom Houben

Research Interests

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About

Articles (18)

Plasma cathepsin D as an early indicator of alcohol-related liver disease

Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction-associated steatohepatitis.

Lipids in major depressive disorder: new kids on the block or old friends revisited?

Elevated granulocyte-colony stimulating factor and hematopoietic stem cell mobilization in Niemann-Pick type C1 disease

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

The Influence of a Conjugated Pneumococcal Vaccination on Plasma Antibody Levels against Oxidized Low-Density Lipoprotein in Metabolic Disease Patients: A Single-Arm Pilot Clinical Trial

Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment

Insulin resistance is positively associated with plasma cathepsin D activity in NAFLD patients

Anti-Inflammatory Effects of Dietary Plant Stanol Supplementation Are Largely Dependent on the Intake of Cholesterol in a Mouse Model of Metabolic Inflammation

Cysteamine Decreases Low-Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low-Density Lipoprotein Receptor-Deficient Mice.

OxLDL as an Inducer of a Metabolic Shift in Cancer Cells.

Myosteatosis in NAFLD patients correlates with plasma Cathepsin D.

Glial contribution to cyclodextrin-mediated reversal of cholesterol accumulation in murine NPC1-deficient neurons in vivo.

Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals.

<i>The Ins and Outs of Cathepsins</i>: Physiological Function and Role in Disease Management.

Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling.

Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease.

Nonalcoholic Fatty Liver Disease.

Collaborators (4)

Klary E. Niezen-Koning

Dennis Meesters

Ronit Shiri-Sverdlov

Jan Theys

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