Jan Theys at Maastricht University - Research Interests, Publications & Academic Profile

Jan Theys

University of Maastricht

Netherlands

Has grant

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Research Interests

Microbiology

30%

Immunology

20%

Microbial Biotechnology

20%

Gut Microbiota

20%

Enzyme Replacement Therapy

20%

Inflammation

10%

Deep Learning

10%

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Recent Grants

Grant: Close

Tumour-targeting bacteria as immune stimulants for cancer immunotherapy

Open Date: 2023-01-01

Close Date: 2026-01-01

Articles10

A novel orthotopic mouse model replicates human lung cancer cachexia

Article Link

Year:

2023

Clostridia as live biotherapeutics: can modified Clostridium species enhance disease treatments?

Article Link

Year:

2023

Heterologous Gene Regulation in Clostridia

Article Link

Year:

2022

Selectively Targeting Tumor Hypoxia with the Hypoxia-Activated Prodrug CP-506

Article Link

Year:

2021

COVID‐19 infection, progression, and vaccination: Focus on obesity and related metabolic disturbances

Article Link

Year:

2021

Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans

Article Link

Year:

2021

Inhibition of Extracellular Cathepsin D Reduces Hepatic Lipid Accumulation and Leads to Mild Changes in Inflammationin NASH Mice

Article Link

Year:

2021

Efficient Secretion of Murine IL-2 From an Attenuated Strain of Clostridium sporogenes, a Novel Delivery Vehicle for Cancer Immunotherapy

Article Link

Year:

2021

Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy.

Article Link

Year:

2021

Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours.

Article Link

Year:

2021

Collaborators9

Tom Houben

Assistant Professor

NETHERLANDS

Amir Ashoorzadeh

University of Auckland

NEW ZEALAND

Brent van der Heyden

Assistant Professor

Ghent University

BELGIUM

Ludwig J. Dubois

University of Maastricht

NETHERLANDS

David Ackerley

Professor and Programme Director, Biotechnology

Victoria University of Wellington

NEW ZEALAND

Ronit Shiri-Sverdlov

University of Maastricht

NETHERLANDS

Philippe Lambin

University of Maastricht

NETHERLANDS

Adam Patterson

Associate Professor

University of Auckland

NEW ZEALAND

Ardy van Helvoort

Associate Professor

University of Maastricht

NETHERLANDS

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