Ton Rabelink

professor

Leiden University

Netherlands

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About

Ton Rabelink is a professor at Leiden University in the Netherlands. His research focuses on kidney transplantation, including organ perfusion, metabolic changes after stroke, and endothelial dysfunction in aging kidneys. He has published extensively on topics such as single cell transcriptomics, non-invasive imaging techniques, and novel treatments for kidney diseases.

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2022

Collaborators (16)

Frits Rosendaal

Leiden University

NETHERLANDS

Ton Rabelink

Research Interests

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Articles (30)

Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke

Improving outcomes in kidney transplantation through advances in donor organ perfusion.

Non-invasive characterization of pericyte dysfunction in mouse brain using functional ultrasound localization microscopy.

Normothermic human kidney preservation drives iron accumulation and ferroptosis.

Opportunities and challenges with the implementation of normothermic machine perfusion in kidney transplantation.

Single cell transcriptomics of human kidney organoid endothelium reveals vessel growth processes and arterial maturation upon transplantation.

Design and &lt;i&gt;In Vitro&lt;/i&gt; Evaluation of a Novel Antisense Oligonucleotide for Treatment of BK Virus Infection.

Clinically compliant enrichment of human pluripotent stem cell-derived islets.

Defibrillation Threshold Testing After ICD Implantation in Patients with Chronic Kidney Disease.

Endothelial dysfunction in the aging kidney.

Hypertension and diabetes, but not leptin and adiponectin, mediate the relationship between body fat and chronic kidney disease

Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system

Application of spatial-omics to the classification of kidney biopsy samples in transplantation.

Spatial metabolomics in tissue injury and regeneration.

A cell-free nutrient-supplemented perfusate allows four-day ex vivo metabolic preservation of human kidneys.

Disruption of memory B-cell trafficking by belimumab in patients with systemic lupus erythematosus.

Long-term renal and cardiovascular risks of tacrolimus in patients with lupus nephritis.

Endothelial to mesenchymal transition in kidney fibrosis.

Role of dietary interventions on microvascular health in South-Asian Surinamese people with type 2 diabetes in the Netherlands: A randomized controlled trial.

Evidence from the large VALIGA cohort validates the subclassification of focal segmental glomerulosclerosis in IgA nephropathy.

Altered high‐density lipoprotein composition is associated with risk for complications in type 2 diabetes mellitus in South Asian descendants: A cross‐sectional, case‐control study on lipoprotein subclass profiling

Phosphatidylinositol metabolism of the renal proximal tubule S3 segment is disturbed in response to diabetes

Glomerular endothelial glycocalyx-derived heparan sulfate inhibits glomerular leukocyte influx and attenuates experimental glomerulonephritis.

Replacing renal function using bioengineered tissues

Peroxisome proliferator-activated receptor ɣ agonist mediated inhibition of heparanase expression reduces proteinuria.

Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos.

Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids.

Preliminary Assessment of Safety and Tolerability of Avacopan During the Early Access Program for ANCA-Associated Vasculitis.

Clinical value and cost analysis of the sFlt-1/PlGF ratio in addition to the spot urine protein/creatinine ratio in women with suspected pre-eclampsia: PREPARE cohort study.

Ethnic differences in urinary monocyte chemoattractant protein-1 and heparanase-1 levels in individuals with type 2 diabetes: the HELIUS study.

Collaborators (16)

Frits Rosendaal

Martin Giera

Ruifang Li-Gao

Ko Willems van Dijk

Hildo J Lamb

Richard Davis

Arnaud Zaldumbide

Elisabeth van Rossum

GANGQI WANG

Françoise Carlotti

Thomas Minor

Y K Onno Teng

Bernard van den Berg

Friedo Dekker

Hanno Pijl

Maria Letizia Lo Faro

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Design and <i>In Vitro</i> Evaluation of a Novel Antisense Oligonucleotide for Treatment of BK Virus Infection.