Martin Giera

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Assoc. Prof.

Universitair Medisch Centrum Utrecht

Netherlands

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About

Martin Giera is an Associate Professor at Leids Universitair Medisch Centrum in the Netherlands. His research areas include metabolomics, platelet activation, and the impact of lipids on thrombotic risk and metabolic diseases. Recent articles by Professor Giera focus on the metabolic reprogramming after stroke and the role of de novo lipogenesis in viral assembly and release.

Recent Grants

Grant: Close

The Neurolipid Atlas

Open Date: 2021-01-01

Close Date: 2023-08-01

Grant: Close

ArthritisHeal

Open Date: 2019-03-01

Close Date: 2023-01-01

Grant: Close

Dehydrocholesterol reductase 24 a possible target for the treatment of nonalcoholic steatohepatitis?

Open Date: 2018-01-01

Close Date: 2019-01-01

Grant: Close

Determining the underappreciated role of lipid metabolism in MSC-mediated immunomodulation.

Open Date: 2018-01-01

Close Date: 2019-01-01

Grant: Close

In-depth mapping of the species-lipidome in the kefir community

Open Date: 2015-01-01

Close Date: 2016-01-01

Articles (29)

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2023

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2023

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2023

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2023

Collaborators (37)

Per-Johan Jakobson

Professor

Karolinska Institutet

SWEDEN

Martin Giera

Research Interests

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About

Recent Grants

Articles (29)

Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry

Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles

Deleting ACC1 in platelets alters phospholipidome and reduces platelet activation and thrombosis in mice

Spatial quantitative metabolomics enables identification of remote and sustained ipsilateral cortical metabolic reprogramming after stroke

Metabolomic Profiles of Oral Rinse Samples to Distinguish Severe Periodontitis Patients From Non‐Periodontitis Controls

Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis

Label-free quantitative shotgun analysis of bis(monoacylglycero)phosphate lipids

iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments

Hematopoietic stem cell metabolism within the bone marrow niche – insights and opportunities

Relevance of plasma lipoproteins and small metabolites in assessment of nutritional status among patients with severe injuries

XCMS-METLIN: data-driven metabolite, lipid, and chemical analysis

Integration of mass cytometry and mass spectrometry imaging for spatially resolved single-cell metabolic profiling

Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles

The ORP9-ORP11 dimer promotes sphingomyelin synthesis

The ORP9-ORP11 dimer promotes sphingomyelin synthesis

iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments

Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis.

Macrophage-mediated myelin recycling fuels brain cancer malignancy.

Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice

Altered high‐density lipoprotein composition is associated with risk for complications in type 2 diabetes mellitus in South Asian descendants: A cross‐sectional, case‐control study on lipoprotein subclass profiling

Altered high-density lipoprotein composition is associated with risk for complications in type 2 diabetes mellitus in South Asian descendants: A cross-sectional, case-control study on lipoprotein subclass profiling

Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation

Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation

Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation

Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation

Membrane lipid remodeling modulates γ-secretase processivity

Membrane lipid remodeling modulates gamma-secretase processivity

Novel determinant of antibiotic resistance: a clinically selected Staphylococcus aureus clpP mutant survives daptomycin treatment by reducing binding of the antibiotic and adapting a rod-shaped morphology

Translational characterization of the temporal dynamics of metabolic dysfunctions in liver, adipose tissue and the gut during diet-induced NASH development in Ldlr−/−.Leiden mice

Collaborators (37)

Per-Johan Jakobson

Francisco Schopfer

Johan Heemskerk

Anna Nicolaou

Ning Qing Liu

Peter Collins

Lars Verschuren

Edward A Dennis

Ruifang Li-Gao

José Inia

Gerhard Liebisch

Yassene Mohammed

Irundika Dias

Hildo J Lamb

Sarantos Kostidis

Julijana Ivanisevic

Gary Siuzdak

Charles N. Serhan

J. Wouter Jukema

Ulrike Garscha

Louis Schmidt

Noel de Miranda

Bruce Freeman

Ton Rabelink

Ruth Andrew

Makoto Arita

Bruno Guigas

Roman Koning

Bernard van den Berg

Eric Snijder

Ameer Taha

Oswald Quehenberger

Marieke Ijsselsteijn

Michael Murphy

Ivana Milic

A. Mahfouz

Robert K Hofstetter

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