Tsutomu Sasaki

教授 / Professor

Kyoto University

Japan

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Tsutomu Sasaki is a Professor at Kyoto University, Japan. His research areas include lipid metabolism, obesity, and metabolic disorders, with recent articles focusing on topics such as medium-chain fatty acid β-oxidation, the role of FTO in weight gain, and the effects of fibroblast growth factor 21 on obesity. He investigates the molecular mechanisms underlying glucose intolerance and energy metabolism, contributing to advancements in understanding metabolic diseases.

Articles (20)

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2025

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2021

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2021

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2021

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2021

Collaborators (12)

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Tsutomu Sasaki

Research Interests

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Articles (20)

Defective medium-chain fatty acid β-oxidation in the liver alters the fat preference and induces hepatic steatosis and glucose intolerance

FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons

(+)-Terrein exerts anti-obesity and anti-diabetic effects by regulating the differentiation and thermogenesis of brown adipocytes in mice fed a high-fat diet

Promotion of obesity by fibroblast growth factor 21-oxytocin system dysfunction due to sugar-specific hyperphagia

MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes

Impaired cardiac branched-chain amino acid metabolism in a novel model of diabetic cardiomyopathy.

Exposure to mouse dams to bonito broth during gestation or lactation reduces fat intake in offspring

Adaptive gene expression of alternative splicing variants of PGC-1α regulates whole-body energy metabolism.

Medium-Chain Triglycerides-Specific Appetite is Regulated by the β-oxidation of Medium-Chain Fatty Acids in the Liver.

Binding Interaction Between Lauric Acid and Cluster of Differentiation 36 Underpinned by a Fluorescence-Intensifying Assay

Application of a novel fluorescence intensity assay: identification of distinct fatty acetates as volatile compounds that bind specifically to amino acid region 149-168 of a transmembrane receptor CD36.

Application of a novel fluorescence intensity assay: identification of distinct fatty acetates as volatile compounds that bind specifically to amino acid region 149-168 of a transmembrane receptor CD36

Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium

Role of SIRT1 and Progesterone Resistance in Normal and Abnormal Endometrium

The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic-Pituitary-Thyroid Axis for Regulating Thyroid Hormone Levels

The Hypothalamic Paraventricular Nucleus Is the Center of the Hypothalamic-Pituitary-Thyroid Axis for Regulating Thyroid Hormone Levels.

Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice

Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury.

Urinary FABP1 is a biomarker for impaired proximal tubular protein reabsorption and is synergistically enhanced by concurrent liver injury

Collaborators (12)

Tadahiro Kitamura

Winda Ariyani

KAZUTO OHASHI

Takahiro Horie

Yasuo Oguri

Jae-Wook Jeong

Bruce Lessey

Atsuo Sasaki

Takehiko Sasaki

Kazuhiro Omori

Ayumu Konno

Tatsuya Iso

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