Urs Jenal

The Jenal Lab at the Biozentrum, University of Basel, is seeking a highly motivated postdoctoral researcher for a project in rational anti-biofilm drug development. This position focuses on structure-based design to develop new anti-biofilm compounds, starting from a resolved target–ligand complex in Pseudomonas aeruginosa . The successful candidate will design and test next-generation molecules with broader activity against WHO priority pathogens, including Escherichia coli , Klebsiella pneumoniae , and Acinetobacter baumannii . The research is at the interface of structural biology, microbiology, and chemistry, and is embedded within the National Centre of Competence in Research (NCCR) AntiResist. The group uses state-of-the-art organoid technology, advanced microscopy, omics, and a variety of cellular and molecular microbiology assays to understand human infections and foster antibiotic discovery. The Biozentrum is a leading life sciences institute with a vibrant international research community and excellent infrastructure. Applicants should have a PhD in Molecular Biology, Microbiology, Biochemistry, or Structural Biology, with relevant research experience. The position is initially for one year, with the possibility of extension, and offers salary and benefits according to University of Basel standards. The application process requires a brief personal statement, CV, diplomas, and two reference letters. Applications are reviewed on a rolling basis until the position is filled. For more information and to apply, visit the Biozentrum's open positions page. Informal inquiries can be directed to Jenal-Recruitment at unibas.ch.

The Jenal Lab at the Biozentrum, University of Basel, is recruiting a postdoctoral researcher for a project focused on the rational development of anti-biofilm drugs targeting human pathogens. The Biozentrum is a world-renowned life sciences institute, offering a vibrant, international research environment with state-of-the-art infrastructure. The successful candidate will join a dynamic team embedded in the National Centre of Competence in Research (NCCR) AntiResist, working at the forefront of infection biology and antibiotic discovery. The project leverages advanced organoid technology and a variety of cellular and molecular microbiology assays, including microscopy and omics approaches, to understand human infections, host responses, and drug treatments. The main goal is to design, develop, and test novel anti-biofilm compounds with broad activity against WHO priority pathogens such as Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii, building on structural data from Pseudomonas aeruginosa. The postdoc will collaborate within a trans-national consortium of experts in structure-based modelling, structural biology, and chemistry. Applicants should have a PhD in Molecular Biology, Microbiology, Biochemistry, or Structural Biology, and demonstrate research experience in these fields. The position is initially for one year, with the possibility of extension, and offers salary and benefits according to University of Basel standards. Basel is a major European life sciences hub, providing a high standard of living and a rich cultural atmosphere. Applications should be submitted online, including a personal statement, CV, diplomas, and two reference letters. Informal inquiries can be directed to Professor Urs Jenal at [email protected]. Review of applications will begin immediately and continue until the position is filled.

The Jenal Lab at the Biozentrum, University of Basel, is recruiting a postdoctoral researcher to investigate the role of signal transduction in E. coli bacteriophage infection and defence. The Biozentrum is a world-leading life sciences institute, home to 32 research groups and 500 employees, and is renowned for its contributions to biology and medicine. The Jenal Lab is part of the National Centre of Competence in Research (NCCR) AntiResist, which focuses on understanding human infections and fostering antibiotic discovery using advanced organoid technology. The research project centers on elucidating the function of the second messenger c-di-GMP in E. coli bacteriophage infection and propagation, and exploring host mechanisms that enable escape from phage killing by modulating signal transduction pathways. The successful candidate will join a dynamic, interdisciplinary team with expertise in molecular biology, microbiology, infection biology, and will collaborate with researchers in structural and computational biology. The lab employs a wide range of techniques, including cellular and molecular microbiology, advanced microscopy, and omics approaches, to achieve a detailed understanding of infection processes, host responses, and drug treatments. Applicants should hold a PhD in Molecular Biology, Microbiology, Biochemistry, or related fields, and have relevant research experience. The position is initially for one year, with the possibility of extension, and offers salary and benefits according to University of Basel standards. The Biozentrum provides a cutting-edge research environment and excellent working conditions. Basel is an international city at the crossroads of Switzerland, Germany, and France, and is recognized as Europe's most important life sciences hub, offering a high standard of living and a vibrant cultural scene. Applications should be submitted online, including a personal statement, CV, diplomas, and two reference letters. Review of applications will begin immediately and continue until the position is filled. Informal inquiries can be directed to [email protected].