Václav Němec

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Goethe University Frankfurt

Germany

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Jean Marie Lehn Price for Chemistry 2019

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Articles (10)

Year:

2025

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2025

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2024

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2024

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2024

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2023

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2022

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2021

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2021

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2020

Collaborators (6)

Xinlai Cheng

GERMANY

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Kamil Paruch

CZECH REPUBLIC

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Lap Hang Tse

University of Oxford

UNITED KINGDOM

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Pavel Krejci

Assitant professor, Lab leader

Masaryk University

CZECH REPUBLIC

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Julien Cros

Institut Pasteur

FRANCE

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Paula Moyano

Assistant Professor

Universidad Complutense de Madrid

SPAIN

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Václav Němec

Research Interests

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Contact this professor

Recent Grants

Articles (10)

Discovery of an exquisitely selective WDR5 chemical probe accelerated by a high-quality DEL–ML Hit

Workflow for E3 Ligase Ligand Validation for PROTAC Development

Discovery of Two Highly Selective Structurally Orthogonal Chemical Probes for Activin Receptor-like Kinases 1 and 2

Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε

A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7

Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity

PROTAC degraders as chemical probes for studying target biology and target validation

A Chemical Toolbox for Labeling and Degrading Engineered Cas Proteins

Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core

Cdc-Like Kinases (CLKs): Biology, Chemical Probes, and Therapeutic Potential

Collaborators (6)

Xinlai Cheng

Kamil Paruch

Lap Hang Tse

Pavel Krejci

Julien Cros

Paula Moyano

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