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Vito D'Agostino
Associate Professor
ItalyResearch Interests
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Articles (15)
Year:
2026
Year:
2025
Head and Neck Squamous Cell Carcinoma (HNSCC) is a malignant cancer with a poor prognosis. Galectins (Gal) have been the subject of intensive research, but the comparative prognostic value of each Gal type is not yet understood. Therefore, a literature search for evaluating galectins as prognostic biomarkers in HNSCC was conducted. The relationship between Gal expression in HNSCC with HPV and TP53 mutational status was assessed using the UALCAN database. The impact of these biomarkers on prognosis was analyzed using ToPP and CPPA web tools. The expression of galectins in the tumor microenvironment and the impact on prognosis depending on the cancer immune subtype were analyzed using single-cell RNA sequencing. Gal-1 and Gal-3BP were shown to be promising biomarkers with a triple function for the prediction of HPV and TP53 mutational status, stratification of the HNSCC prognosis, and prediction of the response to treatment. In addition, these two galectins have been shown to be most influenced by the tumor microenvironment of HNSCC. Gal-1 and Gal-3BP are the most promising galectins in HNSCC. Furthermore, this study highlights the need for further studies to evaluate galectins in HNSCC and clarify the role of individual Gals in the patient’s stratification.
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2023
Year:
2023
Year:
2023
Collaborators (53)
VIKRAMSINGH GUJAR
Assistant Professor
University of Oklahoma Health Sciences Center
Rui Vitorino
Principal Investigator
Universidade de Aveiro
Berglind Eva Benediktsdottir
Associate Professor
University of Iceland
Luke van der Koog
Scientific Staff, Other Scientific Research Staff, Onderzoeker
University of Groningen
Subhadip Ghatak
Associate Professor
University of Pittsburgh
Graziano Lolli
Associate professor
University of Trento
Attila Oláh
University of Debrecen
Sabina Górska
Head of the Microbiome Immunobiology Laboratory/PhD
Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
Manuela Basso
Assistant professor
-
Giulia Girolimetti
Università del Salento
Diego Kyburz
Head of Department
University Hospital Basel
Orsetta Quaini
University of Trento
Andrea Defant
University of Trieste
Daniela Freitas
Project Leader
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
Ágata Carreira
University of Oxford
Marca Wauben
Professor Intercellular Communication
Utrecht University
Max Piffoux
Hospices Civils de Lyon
Marta Garcia-Contreras
University of Miami School of Medicine
Sukhbir Kaur
Associate Scientist
National Institutes of Health
Jennifer Jones
Investigator; Head, Translational Nanobiology Section
National Cancer Institute
Christian Neri
INSERM
Dennis Jeppesen
Assistant Professor
Vanderbilt University School of Medicine
Nicolò Gualandi
San Raffaele Telethon Institute for Gene Therapy
Rita Ferreira
Assistant Professor
Universidade de Aveiro
Denise Sighel
teaching
Università degli Studi di Torino
Álvaro Compañ Bertomeu
PDI
Valencian International University
Ram Sagar
Research Associate (Faculty Member)
Johns Hopkins University School of Medicine
Igea D'Agnano
Senior scientist
Consiglio Nazionale delle Ricerche
Sheref Mansy
Professor
University of Alberta
Nilufar Ali
Assistant Research Professor
Boise State University
Júlia Costa
Principal Investigator, Group Leader
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Julie Constanzo
Research Scientist (CRCN INSERM)
INSERM
Benedetta Bussolati
Full Professor of Laboratory Medicine
University of Turin
Dorival Mendes Rodrigues-Junior
Researcher Docent
Uppsala University
Aled Clayton
Professor of Cancer Studies
Cardiff University
Ines Mancini
University of Trento
Jonathan Degosserie
Co-Head of Molecular Biology
CHU UCL Namur
Shiro Suetsugu
Professor
Nara Institute of Science and Technology（NAIST）
Luis Mariñas-Pardo
Head of Cell Therapies Unit
Instituto de Salud Carlos III
Jonathan Leor
Professor
Tel Aviv University
Emiliano Dalla
Università degli Studi di Udine
Stuart Hunt
Senior lecturer
University of Sheffield
Dorian Forte
Assistant Professor (junior)
University of Bologna
Catherine Martel
Full Professor
Université de Montréal
Carmen Campos-Silva
Personal Docente e Investigador
Universidad Loyola Andalucía
Tara Thompson-Felix
Assistant Professor
Yale University
Maria D Mayan
Research Group Leader
Universidade de Vigo
Muhammad Nawaz
University of Salzburg
Aleksandra Inic-Kanada
Medical University of Vienna
Miroslaw Kornek
Saarland University Medical Center
Sarah Glass
Research Assistant Professor
UPMC Hillman Cancer Center
Gi-Hoon Nam
Assistant Professor
Korea University
Anna Antoniou
Universität Wien
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