Wytske M. van Weerden

Erasmus University Medical Center

Netherlands

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Research Interests

Cell Biology

50%

Pharmacology

90%

Cancer Biology

90%

Prostate Cancer

60%

Xenograft Models

40%

Steroid Chemistry

30%

Cancer Research

30%

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Articles20

Reticuloendothelial system blockade does not enhance siRNA-LNP circulation or tumor accumulation in mice

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Year:

2025

Darolutamide does not interfere with OATP‐mediated uptake of docetaxel

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Year:

2024

Defining the challenges and opportunities for using patient‐derived models in prostate cancer research

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Year:

2024

Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells

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Year:

2024

Capivasertib combines with docetaxel to enhance anti-tumour activity through inhibition of AKT-mediated survival mechanisms in prostate cancer

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Year:

2024

Darolutamide added to docetaxel augments antitumor effect in models of prostate cancer through cell cycle arrest at the G1-S transition

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Year:

2024

Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites

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Year:

2024

The future of patient-derived xenografts in prostate cancer research

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Year:

2023

Viability Analysis and High-Content Live-Cell Imaging for Drug Testing in Prostate Cancer Xenograft-Derived Organoids

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Year:

2023

Androgen receptor mutations modulate activation by 11-oxygenated androgens and glucocorticoids

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Year:

2023

Awe and anxiety for cancer cells: connecting scientists and patients in a holistic approach of metastasis research

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Year:

2023

GRPR versus PSMA

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Year:

2023

Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling

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Year:

2022

Preclinical Assessment of the Combination of PSMA-Targeting Radionuclide Therapy with PARP Inhibitors for Prostate Cancer Treatment

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Year:

2022

Abiraterone switches castration‐resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling

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Year:

2022

Radiolabeled Bombesin Analogs

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Year:

2021

Modeling Prostate Cancer Treatment Responses in the Organoid Era: 3D Environment Impacts Drug Testing

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Year:

2021

Patient-Derived Xenograft Models in Cancer Research

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Year:

2021

The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel‐resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe

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Year:

2020

NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice—A Novel in Vivo Imaging Platform

Article Link

Year:

2020

Collaborators15

Elena Martens-Uzunova

Erasmus University Rotterdam

NETHERLANDS

Stefan Buck

NETHERLANDS

Jack A. Schalken

NETHERLANDS

Shuiying Hu

Ohio State University

UNITED STATES

Guido Jenster

Professor Experimental Urological Oncology

Erasmus MC

NETHERLANDS

Simone Dalm

Assistant Professor, PI

Erasmus MC

NETHERLANDS

Pim French

Assoc Prof

Erasmus MC

NETHERLANDS

Dik C. van Gent

Erasmus University Rotterdam

NETHERLANDS

W. Nathaniel Brennen

Associate Professor

Johns Hopkins University School of Medicine

UNITED STATES

Renea Taylor

MONASH UNIVERSITY

AUSTRALIA

Martin van Royen

Assistant Professor

Erasmus MC

NETHERLANDS

Natalie Lister

MONASH UNIVERSITY

AUSTRALIA

Hub Zwart

Full professor and Dean

Erasmus University Rotterdam

NETHERLANDS

Harmen van de Werken

Assistant Professor Computational Biology & Bioinformatics at the Department of Immunology

Erasmus MC

NETHERLANDS

Jan Bouchal

Palacký University, Olomouc

CZECH REPUBLIC

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