Xuezhi Bi

Associate Professor (Adjunct)

Duke-NUS Medical School

Singapore

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About

Xuezhi Bi is an Associate Professor (Adjunct) at Duke-NUS Medical School in Singapore. His research focuses on antibody-based therapeutics, T-cell differentiation, and the production of monoclonal antibodies. Recent publications explore various aspects of cell culture systems, including the physicochemical properties of proteins and the effects of metabolic changes during cellular responses. He contributes significantly to the fields of proteomics and cell biology, facilitating advancements in medical research.

Articles (15)

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2025

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2024

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (8)

Gloryn Chia

Assistant Professor

National University of Singapore

SINGAPORE

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Hwee Tong Tan

SINGAPORE

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Lin Zhao

Singapore Institute of Technology

SINGAPORE

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Sultan Abda Neja

Texas A&M University

UNITED STATES

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Navin Kumar Verma

Assistant Professor of Immunology and Cell Biology

Nanyang Technological University (NTU)

SINGAPORE

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Derrick Ong

Assistant Professor

National University of Singapore (NUS)

SINGAPORE

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Stephen Tate

Chief Research Scientist

CANADA

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Juan Du

Associate Professor

Singapore Institute of Technology

SINGAPORE

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Xuezhi Bi

Research Interests

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About

Articles (15)

Multilevel─Intact, Subunits, and Peptides─Characterization of Antibody-Based Therapeutics by a Single-Column LC–MS Setup

Temporal insights into molecular and cellular responses during rAAV production in HEK293T cells

Effects of molecule hydrophobicity and structural flexibility of appended bispecific antibody on Protein A chromatography

High Extracellular K<sup>+</sup> Skews T-Cell Differentiation Towards Tumour Promoting Th2 and T<sub>reg</sub> Subsets.

SWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells

Physicochemical properties, structural characteristics and in vitro digestion of brown rice–pea protein isolate blend treated by microbial transglutaminase

Cottonseed Meal Protein Isolate as a New Source of Alternative Proteins: A Proteomics Perspective

SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer

A synbiotic intervention modulates meta-omics signatures of gut redox potential and acidity in elective caesarean born infants

Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality

Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts

Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library

A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins

Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells

Collaborators (8)

Gloryn Chia

Hwee Tong Tan

Lin Zhao

Sultan Abda Neja

Navin Kumar Verma

Derrick Ong

Stephen Tate

Juan Du

Make your next move.

Xuezhi Bi

Research Interests

Contact this professor

About

Articles (15)

Multilevel─Intact, Subunits, and Peptides─Characterization of Antibody-Based Therapeutics by a Single-Column LC–MS Setup

Temporal insights into molecular and cellular responses during rAAV production in HEK293T cells

Effects of molecule hydrophobicity and structural flexibility of appended bispecific antibody on Protein A chromatography

High Extracellular K&lt;sup&gt;+&lt;/sup&gt; Skews T-Cell Differentiation Towards Tumour Promoting Th2 and T&lt;sub&gt;reg&lt;/sub&gt; Subsets.

SWATH-MS insights on sodium butyrate effect on mAbs production and redox homeostasis in CHO cells

Physicochemical properties, structural characteristics and in vitro digestion of brown rice–pea protein isolate blend treated by microbial transglutaminase

Cottonseed Meal Protein Isolate as a New Source of Alternative Proteins: A Proteomics Perspective

SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer

A synbiotic intervention modulates meta-omics signatures of gut redox potential and acidity in elective caesarean born infants

Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality

Tmod3 Phosphorylation Mediates AMPK-Dependent GLUT4 Plasma Membrane Insertion in Myoblasts

Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library

A comprehensive CHO SWATH-MS spectral library for robust quantitative profiling of 10,000 proteins

Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells

Collaborators (8)

Gloryn Chia

Hwee Tong Tan

Lin Zhao

Sultan Abda Neja

Navin Kumar Verma

Derrick Ong

Stephen Tate

Juan Du

Make your next move.

High Extracellular K<sup>+</sup> Skews T-Cell Differentiation Towards Tumour Promoting Th2 and T<sub>reg</sub> Subsets.