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Yu Heng Lau

Associate Professor

University of Sydney

Australia

Research Interests

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About

Dr. Yu Heng Lau is a Senior Lecturer at The University of Sydney, Australia. His research primarily focuses on the structural and supramolecular chemistry of protein cages and virus-like particles, as well as their interactions with telomerase and cellular mechanisms. Recent articles highlight his contributions to understanding molecular flux in engineered protein compartments and the development of innovative synthetic cargo systems.

Articles (18)

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2026

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2025

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2021

Collaborators (8)

Reidun Twarock

Professor of Mathematical Biology

University of York

UNITED KINGDOM

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Hilda A. Pickett

University of Sydney

AUSTRALIA

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Frank Sainsbury

AUSTRALIA

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Scott B Cohen

Senior Research Scientist

Children's Medical Research Institute

AUSTRALIA

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Andrew Care

Macquarie University

AUSTRALIA

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Tracy M. Bryan

University of Sydney

AUSTRALIA

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Tobias Giessen

Associate Professor

University of Michigan Medical School

UNITED STATES

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Lisa Alcock

Lecturer

Curtin University

AUSTRALIA

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Yu Heng Lau

Research Interests

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About

Articles (18)

Using generative AI to transform peptide hits into small molecule leads

High-Fidelity In Vitro Packaging of Diverse Synthetic Cargo into Encapsulin Protein Cages.

NONO, SFPQ, and PSPC1 promote telomerase recruitment to the telomere

Cell-Active Peptide Inhibitors of the FANCM-RMI Interaction

Reprogramming encapsulins into modular carbon-fixing nanocompartments

Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages

Accessing diverse bicyclic peptide conformations using 1,2,3-TBMB as a linker

Development of stapled NONO‐associated peptides reveals unexpected cell permeability and nuclear localisation

Mannich Base PIP-199 Is a Chemically Unstable Pan-Assay Interference Compound

Structural polymorphism in protein cages and virus-like particles

The supramolecular chemistry of protein cages and viruses

How Pore Architecture Regulates the Function of Nanoscale Protein Compartments

Pore structure controls stability and molecular flux in engineered protein cages

Front Cover: Molecular Display on Protein Nanocompartments: Design Strategies and Systems Applications (ChemSystemsChem 1/2022)

Molecular Display on Protein Nanocompartments: Design Strategies and Systems Applications

Molecular Display on Protein Nanocompartments: Design Strategies and Systems Applications

Artificial Self-assembling Nanocompartment for Organizing Metabolic Pathways in Yeast

Cyclisation strategies for stabilising peptides with irregular conformations

Collaborators (8)

Reidun Twarock

Hilda A. Pickett

Frank Sainsbury

Scott B Cohen

Andrew Care

Tracy M. Bryan

Tobias Giessen

Lisa Alcock

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