Yuk Sham

University of Minnesota

United States

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Articles (17)

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (7)

Erika Taylor

Associate Professor

Wesleyan University

UNITED STATES

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Walter Schmidt

University of Georgia

UNITED STATES

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Megan Beetch

Research Assistant Professor

University of Minnesota

UNITED STATES

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Woo Shik Shin

Northeast Ohio Medical University

UNITED STATES

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James Hougland

Professor

Syracuse University

UNITED STATES

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Mark D. Distefano

UNITED STATES

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Alessandro Bartolomucci

University of Minnesota

UNITED STATES

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Yuk Sham

Research Interests

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Articles (17)

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Carbapenem-induced β-lactamase-isoform expression trends in Acinetobacter baumannii

In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT-B Glycosyltransferase

Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism

A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

Characterization of a novel inhibitor for the New Delhi metallo-β-lactamase-4

Kinetic Characterization and Computational Modeling of Escherichia coli Heptosyltransferase II: Exploring the Role of Protein Dynamics in Catalysis for GT-B Glycosyltransferase

Facile and Adaptable Synthesis of a Prazosin Analogue Library: Bringing Medicinal Chemistry into the Undergraduate Curriculum

Ligand-Induced Conformational and Dynamical Changes in a GT-B Glycosyltransferase: Molecular Dynamics Simulations of Heptosyltransferase I Complexes

Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action

Conserved Conformational Hierarchy across Functionally Divergent Glycosyltransferases of the GT-B Structural Superfamily as Determined from Microsecond Molecular Dynamics

The molecular identity of the TLQP-21 peptide receptor

Fragment-based screening and hit-based substructure search

CD200 Immune-Checkpoint Peptide Elicits an Anti-glioma Response Through the DAP10 Signaling Pathway

NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes

Opposites Attract: Escherichia coli Heptosyltransferase I Conformational Changes Induced by Interactions between the Substrate and Positively Charged Residues

Collaborators (7)

Erika Taylor

Walter Schmidt

Megan Beetch

Woo Shik Shin

James Hougland

Mark D. Distefano

Alessandro Bartolomucci

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