Christian Siebold
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NDM Prize Studentships
DPhil Opportunity in Structural Biology of Hedgehog Cell Signalling at the University of Oxford University of Oxford in United Kingdom
Degree Level
PhD
Field of study
Cell Biology
Funding
Available
Deadline
Dec 1, 2026
Country
United Kingdom
University
University of Oxford
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About this position
University of Oxford DPhil in Structural Biology
Christian Siebold’s group at STRUBI, the University of Oxford’s structural biology research environment, is seeking a DPhil student for the 2027 entry through the NDM Prize Studentships scheme.
The project will investigate the structural and molecular mechanisms of Hedgehog signalling within the primary cilium. The student will examine how membrane proteins and signalling complexes function and organise in their cellular environment, addressing signalling processes from atomic to cellular scales. The research has potential implications for understanding cancer and other diseases.
The project combines cutting-edge cryo-electron microscopy, cryo-electron tomography, biochemical methods and cell-based approaches. It offers interdisciplinary training across structural biology, molecular biology, cell biology and biophysics, supported by access to world-class facilities and a collaborative research environment at Oxford.
Funding details
Available
What's required
Applicants should be highly motivated and have a background in biochemistry, molecular biology, cell biology, biophysics, or a related discipline. Previous cryo-EM experience is not essential. Applicants are encouraged to contact Christian Siebold before applying to discuss the project and prepare a strong application.
How to apply
Contact Christian Siebold directly at [email protected] before applying to discuss the project and prepare a strong application. Then apply through the NDM Prize Studentships application process using the project details link.
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Professors
Professor
United Kingdom
Research Interests
Biochemistry
Cell Biology
Lipid Chemistry
Cell Signaling
Molecular Biology
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