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University of East Anglia

PhD Studentship: Investigate How Bacterial Hosts Control Domesticated Viral Machines to Drive Horizontal Gene Transfer in Marine Environments University of East Anglia in United Kingdom

Degree Level

PhD

Field of study

Biochemistry

Funding

Available

Deadline

Dec 16, 2026

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Country

United Kingdom

University

University of East Anglia

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Keywords

Biochemistry
Molecular Biology
Environmental Science
Biology
Marine Biology
Bacterial Genetics
Gene Transfer
Genomic
Bioinformatic

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About this position

[Fully funded studentship covering fees, maintenance stipend (£21,805 p.a. for 2026/27), and a research training and support grant (RTSG). Limited support is available for international applicants via waived home/international fee difference; relocation, visa, and health surcharge costs are not covered.]

PhD Studentship at the University of East Anglia focusing on how bacterial hosts control domesticated viral machines to drive horizontal gene transfer in marine environments.

This project explores gene transfer agents (GTAs), phage-derived particles that package host DNA and transfer it to neighboring cells. The work addresses key questions in bacterial evolution and marine microbial ecology: why bacteria retain GTA systems, how these systems are regulated, how abundant they are in the ocean, and what ecological benefits they provide.

The model organism is Ruegeria pomeroyi DSS-3, a marine Alphaproteobacterium involved in carbon, sulfur, and nitrogen cycling in the phycosphere. The student will study how host regulatory networks control RpGTA production, identify ecological triggers for GTA induction, and quantify the abundance, expression, and diversity of GTAs in marine Roseobacter communities.

Research will combine molecular genetics, cell imaging, marine metagenomics, and metatranscriptomics, including techniques such as ChIP-seq, RNA-seq, Tn-seq, and live-cell imaging. Training is based mainly in the Le lab at the John Innes Centre, with complementary expertise from the Todd lab in marine microbial ecology, metagenomic sampling, and bioinformatics, plus additional mentoring from scientists at JIC, Quadram Institute, and UEA.

Funding is available through the ARIES studentship scheme. Successful UKRI-eligible candidates receive full tuition/fees coverage, a maintenance stipend of £21,805 p.a. for 2026/27, and a research training and support grant. A limited number of studentships are open to international applicants, with the home/international fee difference waived, though relocation, visa, and health surcharge costs are not covered.

Applicants should hold or expect to obtain a first degree in biology, microbiology, or a related discipline.

Apply via the University of East Anglia postgraduate research application portal before 16 December 2026.

Funding details

Available

What's required

Applicants should hold, or expect to obtain, a first degree in biology, microbiology or a related discipline. UKRI eligibility criteria apply for full funding; international applicants may be considered for a limited number of studentships, subject to fee waivers and ARIES/UKRI terms and conditions.

How to apply

Apply through the University of East Anglia postgraduate research application portal. Prepare an application that demonstrates your background in biology, microbiology, or a related field and meets UKRI eligibility requirements. Submit before the deadline of 16 Dec.

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