Metal-based Heterobifunctional Scaffolds to Capture Challenging Proteins The Francis Crick Institute in United Kingdom

University of Bath is recruiting a Postdoctoral Research Associate in an interdisciplinary project focused on mammalian cell biology , molecular biology , chemical biology , and peptide screening . The work will develop innovative intracellular peptide screening technologies to investigate and modulate transcription factor function in living mammalian cells. The post is hosted in Professor Jody Mason's research group at the University of Bath and is funded through a new BBSRC Pioneer Award . The...

Fully funded PhD opportunity in medicinal chemistry at Newcastle University , within the Newcastle Medicinal Chemistry Group. The project focuses on high-throughput chemistry and direct-to-biology screening , with supervision involving Mike Waring and Hannah Stewart, and collaboration with Charles A. and Liz McFaddin at Eli Lilly and Company . This is a research-focused doctoral opening for candidates interested in drug discovery, screening workflows, and modern medicinal chemistry approaches. T...

PhD opportunity at the University of St Andrews in the School of Biology / School of Chemistry, working on design, synthesis, and mechanism of action of inhibitors of the human enzyme DNPH1 (2′-deoxynucleoside 5′-phosphate N-hydrolase 1). This project sits at the interface of Biochemistry , Structural Biology , Medicinal Chemistry , Organic Synthesis , and Chemical Biology . DNPH1 is a nucleotide-sanitizing enzyme, and the project aims to design potent and selective inhibitors and elucidate how ...

Funded PhD project in telomere biology , cancer biology , peptide design , protein biochemistry , molecular biology , cell biology , and synthetic/pharmaceutical chemistry at the MRC Laboratory of Medical Sciences and Imperial College London in London, United Kingdom . The project asks how cells replicate chromosome ends while preserving telomere protection. You will study the shelterin complex, TRF2 interactions, and the origin recognition complex (ORC), with a focus on how disrupting these int...

PhD position no. 20/2026/ICHB/PSD is offered by the Institute of Bioorganic Chemistry, Polish Academy of Sciences, within the Poznań Doctoral School of the Institutes of the Polish Academy of Sciences in Poznań, Poland. The project, led by Dr Weronika Kotkowiak, focuses on modified nucleotide residues as a tool to increase aptamer–target protein interaction. The research is centered on DNA and RNA aptamers, including G-quadruplex and hairpin structures such as RE31, RV66, and Toggle-25t, with th...