Molecular glues and fragment-based drug discovery University of Dundee in United Kingdom

PhD opportunity at the University of St Andrews in the School of Biology / School of Chemistry, working on design, synthesis, and mechanism of action of inhibitors of the human enzyme DNPH1 (2′-deoxynucleoside 5′-phosphate N-hydrolase 1). This project sits at the interface of Biochemistry , Structural Biology , Medicinal Chemistry , Organic Synthesis , and Chemical Biology . DNPH1 is a nucleotide-sanitizing enzyme, and the project aims to design potent and selective inhibitors and elucidate how ...

University of Bath is recruiting a Postdoctoral Research Associate in an interdisciplinary project focused on mammalian cell biology , molecular biology , chemical biology , and peptide screening . The work will develop innovative intracellular peptide screening technologies to investigate and modulate transcription factor function in living mammalian cells. The post is hosted in Professor Jody Mason's research group at the University of Bath and is funded through a new BBSRC Pioneer Award . The...

Funded PhD project at the University of Edinburgh on peptide-based precision anti-infectives for the prophylaxis and prevention of foodborne listeriosis . The project focuses on Listeria monocytogenes , a major foodborne pathogen, and explores a novel anti-virulence strategy targeting the bacterial regulator PrfA . Building on structural and functional discoveries from the Vázquez-Boland group, the PhD will design, synthesise, and evaluate peptide-based PrfA inhibitors as potential Listeria-targ...

The University of Cambridge is inviting applications for PhD research opportunities in synthetic chemistry within the Yusuf Hamied Department of Chemistry. Seven internationally leading research groups offer projects spanning reaction discovery, catalysis, molecular design, chemical biology, supramolecular chemistry, and computation. The research community focuses on inventing new reactions, discovering catalysts, understanding molecular behaviour, and developing tools with applications in biolo...

PhD studentships are available through the University of Strathclyde’s collaborative research partnership with GSK. The opportunity is for PhD research in Medicinal Chemistry , Chemical Biology , and Structural Biophysics , with studentships starting in October 2027 . Funding covers home/UK fees only . The post does not mention a stipend, international fee coverage, or other financial details. The announcement is shared by Laura Paterson, Strathclyde Manager of the Collaborative GSK Research Pro...