Publisher
source

Leiden University

PhD candidate in the Development of Anticancer Nanomedicines Leiden University in Netherlands

Degree Level

PhD

Field of study

Chemistry

Funding

Four-year appointment with competitive salary, holiday and end-of-year bonuses, and support for international candidates. Employees from outside the Netherlands may be eligible for a substantial tax break.

Deadline

Expired

Country flag

Country

Netherlands

University

Leiden University

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Keywords

Chemistry
Biomedical Engineering
Materials Science
Drug Delivery
Biology
Peptide Chemistry
Antibodies
Health Science
Metabolic Syndrome
Polymer Chemistry
Chemical Synthesis
Nanomedicine
Cancer Therapy
Hospital Pharmacy
Polymerization
Amino Acid
Biomedicine

About this position

This PhD position at Leiden University is focused on the development of anticancer nanomedicines within the Faculty of Science and the Leiden Academic Centre for Drug Research (LACDR). The project is part of the NanoMed NL consortium, a collaborative effort among Dutch stakeholders to advance nanomedicine research, integrating fundamental science with the creation of novel therapies for cancer and gene therapies for metabolic disorders. The successful candidate will join the Barz lab, where they will develop polypept(o)ide-based nanomedicines aimed at improving current cancer therapies.

The research involves synthesizing functional amino acids, performing solid phase peptide synthesis, and polymerizing N-carboxyanhydrides to produce precision polymers. These polymers will serve as the foundation for constructing functional nanomedicines, with anticancer drugs covalently attached via disease-responsive bonds. The efficacy of these new systems will be evaluated and compared to conventional antibody drug conjugates (ADCs) within the consortium.

The position offers a stimulating and international research environment located in the heart of the Bio Science Park, with access to advanced training and career development opportunities. The appointment is for four years and includes a competitive salary, holiday and end-of-year bonuses, and support for international candidates, such as a substantial tax break and attractive secondary employment terms. Applicants should possess a strong background in synthetic chemistry, ideally with experience in peptide synthesis, NCA polymerization, or synthetic organic chemistry, and must hold a relevant master's degree.

The application process requires submission of a cover letter, CV, transcripts, and reference letters, followed by an interview and a writing assessment. Leiden University values diversity and inclusion, striving to create a supportive and collaborative academic community.

Funding details

Four-year appointment with competitive salary, holiday and end-of-year bonuses, and support for international candidates. Employees from outside the Netherlands may be eligible for a substantial tax break.

What's required

Applicants must hold a relevant master's degree and have a strong background in synthetic chemistry. Experience in peptide synthesis, N-carboxyanhydride polymerization, or synthetic organic chemistry is highly desirable. Candidates should be able to work in an international research environment and demonstrate motivation for advanced training and career development. Application materials include a cover letter, CV, transcripts, and reference letters. Selection involves an interview and a writing assessment.

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Professors

Prof.

University Name
Country flag

Netherlands

Research Interests

Polymer Chemistry

Polymer Physics

Nanomedicine

Supramolecular Chemistry

Biomedical Engineering