Medical Research Council (Cambridge)
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PhD in AMPA Receptor Structure and Function Medical Research Council (Cambridge) Laboratory of Molecular Biology in United Kingdom
Degree Level
PhD
Field of study
Molecular Biology
Funding
Competition funded PhD project. The post indicates funding is available, but no stipend amount, tuition coverage details, or exact funding package are specified in the text provided.
Deadline
Dec 8, 2026
Country
United Kingdom
University
Medical Research Council (Cambridge)

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About this position
PhD opportunity in AMPA receptor structure and function at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom.
This project sits at the intersection of neuroscience, molecular biology, and structural biology, focusing on how AMPA glutamate receptors (AMPA-Rs) and their auxiliary proteins shape excitatory synaptic transmission, plasticity, and information storage in the brain. The lab aims to decode AMPAR signalling complexity from atomic structure to neural circuits, with an emphasis on receptor composition, trafficking, and synaptic localization.
Two main PhD directions are described: (1) combining patch-clamp electrophysiology, multi-electrode arrays, and super-resolution imaging to study AMPA-R distribution across synapses and recruitment during long-term potentiation (LTP); and (2) using cryo-EM to determine structures of recombinant AMPA-R complexes and native synaptic receptors from different brain regions. The group also explores small-molecule therapeutics targeting AMPA-R auxiliary subunit complexes.
The advert is for a competition-funded PhD project and states that students worldwide may apply. No specific stipend amount, tuition package, or formal eligibility thresholds are listed in the text provided.
To apply, use the FindAPhD project page to register your interest and submit the enquiry form. The university says it will respond directly to applicants.
Funding details
Competition funded PhD project. The post indicates funding is available, but no stipend amount, tuition coverage details, or exact funding package are specified in the text provided.
What's required
Applicants should be interested in molecular neuroscience, structural biology, electrophysiology, cell biology, imaging, and/or cryo-EM. The post is advertised as a competition-funded PhD project for students worldwide; no specific degree class, GPA, or language-test requirement is stated in the text provided.
How to apply
Register your interest through the FindAPhD enquiry form on the project page. The university will respond directly after you submit your details and question.
More information can be found here
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