Publisher
source

Medical Research Council (Cambridge)

PhD in AMPA Receptor Structure and Function Medical Research Council (Cambridge) Laboratory of Molecular Biology in United Kingdom

Degree Level

PhD

Field of study

Molecular Biology

Funding

Competition funded PhD project. The post indicates funding is available, but no stipend amount, tuition coverage details, or exact funding package are specified in the text provided.

Deadline

Dec 8, 2026

Country flag

Country

United Kingdom

University

Medical Research Council (Cambridge)

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Keywords

Molecular Biology
Biology
Structural Biology
Electrophysiology
Cryo-electron Microscopy
Neuropsychology
Medical Science
Synaptic Plasticity
Neural Circuit

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About this position

PhD opportunity in AMPA receptor structure and function at the Medical Research Council (Cambridge), Laboratory of Molecular Biology in the United Kingdom.

This project sits at the intersection of neuroscience, molecular biology, and structural biology, focusing on how AMPA glutamate receptors (AMPA-Rs) and their auxiliary proteins shape excitatory synaptic transmission, plasticity, and information storage in the brain. The lab aims to decode AMPAR signalling complexity from atomic structure to neural circuits, with an emphasis on receptor composition, trafficking, and synaptic localization.

Two main PhD directions are described: (1) combining patch-clamp electrophysiology, multi-electrode arrays, and super-resolution imaging to study AMPA-R distribution across synapses and recruitment during long-term potentiation (LTP); and (2) using cryo-EM to determine structures of recombinant AMPA-R complexes and native synaptic receptors from different brain regions. The group also explores small-molecule therapeutics targeting AMPA-R auxiliary subunit complexes.

The advert is for a competition-funded PhD project and states that students worldwide may apply. No specific stipend amount, tuition package, or formal eligibility thresholds are listed in the text provided.

To apply, use the FindAPhD project page to register your interest and submit the enquiry form. The university says it will respond directly to applicants.

Funding details

Competition funded PhD project. The post indicates funding is available, but no stipend amount, tuition coverage details, or exact funding package are specified in the text provided.

What's required

Applicants should be interested in molecular neuroscience, structural biology, electrophysiology, cell biology, imaging, and/or cryo-EM. The post is advertised as a competition-funded PhD project for students worldwide; no specific degree class, GPA, or language-test requirement is stated in the text provided.

How to apply

Register your interest through the FindAPhD enquiry form on the project page. The university will respond directly after you submit your details and question.

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