PhD in B Cell Antibody Response and Ageing at University of Dundee University of Dundee in United Kingdom

Funded PhD project at the MRC Laboratory of Medical Sciences (LMS) in London, United Kingdom on sex-specific immune responsiveness , with a strong focus on immunology , genetics , molecular biology , bioinformatics , cell biology , and developmental biology . The project, supervised by Prof Matthias Merkenschlager and Dr Lila Allou , investigates why females are often better able to cope with some infections yet are more prone to autoimmune disease. The research centers on Toll-like receptors (T...

Research Degree Opportunity at the University of Melbourne in trogocytosis , immunology , biochemistry , and cell biology . This project investigates how Marginal Zone B cells and Dendritic Cells communicate through a newly discovered mechanism involving Complement C3 and MHC class II molecules, and how excessive trogocytosis can lead to DC death (trogoptosis). The work is offered through the Biochemistry and Pharmacology area in the Faculty of Medicine, Dentistry and Health Sciences, with resea...

PhD opportunity at the University of Dundee in the Faculty of Life Sciences on the project EASTBIO - Uncovering the non-canonical proteolytic activity of Deubiquitinating enzymes . This discovery-driven PhD sits at the interface of biochemistry , structural biology , cell biology , biophysics , and proteomics . The project focuses on ubiquitin-deconjugating enzymes (DUBs), especially the USP family, and their newly identified non-canonical “cleave-to-modify” activity. The research aims to define...

PhD opportunity in immunology and molecular biology at the Medical Research Council (Cambridge), Laboratory of Molecular Biology. The project, supervised by Dr Patrycja Kozic, asks whether perforin-2 (Mpeg1) forms pores in two orientations and how this ancient MACPF/CDC family protein is regulated during immune responses. The research focuses on perforin-2 function in dendritic cells and macrophages, especially its roles in attacking intravacuolar pathogens and enabling cytosolic antigen deliver...

PhD opportunity at the University of Dundee in the Faculty of Life Sciences on SRPK signalling and Alzheimer’s disease . The project, supervised by Dr Greg Findlay and Dr Rosie Jackson , focuses on the neurological functions of the Ser-Arg Protein Kinase (SRPK) family and how dysregulated SRPK signalling contributes to Alzheimer’s disease. The research will map neuronal SRPK substrates and downstream signalling pathways using phosphoproteomic profiling , mass spectrometry , hiPSC-derived neurons...