PhD in Neuroinflammatory Mediators in the Pathophysiology of Traumatic Brain Injury University of Cambridge in United Kingdom

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on retrograde mitochondrial signalling, epigenetic reprogramming, glial toxicity, and neuroinflammation in progressive multiple sclerosis . The project focuses on how mitochondrial dysfunction and mitochondrial stress trigger nuclear signalling and epigenetic changes that may drive astrocytes toward a dysfunctional disease-associated radial glia-like (DARG) phenotype. The work is strongly research-oriented...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on programmed axon death , SARM1 , NMNAT2 , and protein design . The project focuses on understanding the mechanism of programmed axon death, an intrinsic axonal death pathway implicated in neurodegenerative disease and injury. The work will use rational protein design to create variant forms of SARM1 or hybrid reporter constructs to study activation, stability, enzyme activity, and post-translational modi...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Fluid Biomarkers of Inflammation in Frontotemporal Dementia . This project focuses on neuroscience , neurology , neuroinflammation , frontotemporal dementia , and related neurodegenerative disorders, with additional relevance to Alzheimer’s disease , biomarkers , proteomics , neuroimaging , and clinical data analysis. The research aims to characterise inflammation signatures in blood and CSF from people...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Targeting Immune Cell Trafficking to Treat Neurological Disorders . This project focuses on inflammatory peripheral neuropathies , where the immune system attacks peripheral nerves and causes weakness, numbness, pain, and impaired mobility. The research aims to identify whether a specific immune-cell trafficking pathway drives immune-cell accumulation in affected nerves and whether blocking this pathway...

PhD opportunity at the University of St Andrews in the School of Psychology and Neuroscience on descending and ascending control of locomotor and respiratory central pattern generators (CPGs) in health and disease . This project sits at the intersection of neuroscience , neurology , cell biology , and molecular biology , with a strong focus on motor control, respiratory control, and disease-relevant circuit mechanisms. The research will investigate how supraspinal descending pathways and ascendi...