PhD in Replicating RNA with RNA at the Laboratory of Molecular Biology Medical Research Council Laboratory of Molecular Biology in United Kingdom

Funded PhD project at the MRC Laboratory of Medical Sciences (LMS) in London, United Kingdom, in collaboration with Imperial College London and The University of Queensland . The project focuses on bioactive peptides , especially plant-derived cyclic peptides , with research spanning synthetic biology , bioinformatics , biophysics , biochemistry , molecular biology , microbiology , parasitology , entomology , and evolution . The aim is to produce and screen natural peptide sequences at scale, te...

PhD opportunity at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom on mTORC2 activation , AKT signaling , and related biochemistry , cancer biology , and molecular biology questions. The project focuses on how mTORC2 integrates activating inputs to control anabolism, survival, and cytoskeletal remodelling, with emphasis on positive feedback loops and upstream activation mechanisms. The student will help elucidate natural mechanisms of mTORC2 activation a...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...

Fully funded PhD project in AI protein design, structural biology, plant immunity, bioinformatics, biophysics, biochemistry, molecular biology, and plant biology at the University of Cambridge / Bentham Lab network, with co-supervision from Marc Knight . The project aims to design synthetic plant immune receptors from first principles, using generative AI tools such as RFdiffusion, ProteinMPNN and BindCraft, together with structural bioinformatics, X-ray crystallography, cryo-EM, and in planta f...

PhD opportunity at The Francis Crick Institute, London, United Kingdom This funded PhD project with Dr Alessandro Costa focuses on the in situ structure of the replication machinery inside a vertebrate nucleus. The project sits at the intersection of molecular biology , biochemistry , and structural biology , with a strong emphasis on DNA replication initiation, chromatin-associated replication complexes, and the structural mechanisms that control replication once per cell cycle. The research ai...