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PhD Student in Biomarkers, Circadian Rhythms and Huntington’s Disease Lund University in Sweden
Degree Level
PhD
Field of study
Molecular Biology
Funding
This is a full-time, fixed-term doctoral employment for four years. The position provides a monthly salary according to the Faculty’s applicable doctoral student salary scale. Doctoral students are both admitted as students and employed by Lund University, with employee benefits including generous holidays and an occupational pension.
Deadline
Nov 23, 2026
Country
Sweden
University
Lund University
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About this position
Lund University is recruiting a doctoral student to investigate how biological clock disturbances influence Huntington’s disease (HD), an inherited neurodegenerative disorder affecting movement, cognition and psychiatric function.
The project focuses on the relationship between circadian rhythms and disease progression. The body’s biological clock regulates sleep, metabolism, immune function and brain activity, while individual cells and organs maintain their own rhythms. Because sleep and circadian disturbances are common in HD and may contribute to neurodegeneration rather than simply reflect its symptoms, the project will examine whether modifying clock function can alter the course of the disease.
The doctoral student will study the effects of the expanded CAG repeat mutation and huntingtin protein in neuronal and peripheral cells. The research combines in vitro and in vivo experiments with molecular biology, microscopy and RNA sequencing. The role involves balancing hands-on laboratory experimentation with data analysis, including investigation of gene-expression changes and biological-clock mechanisms.
The student will join the Biomarkers in Brain Disease research group within the Department of Experimental Medical Science. The group works on disease mechanisms in the body and brain in Huntington’s disease and is active in the European Huntington’s Disease Network and Lund University Huntington Centre.
The wider workplace brings together five research groups studying neurodegenerative diseases, with approximately 25–30 people sharing equipment, chemicals and joint laboratory meetings. This creates an international and collaborative research environment with opportunities for scientific discussion across related areas of neuroscience and experimental medicine.
The doctoral student may also participate in supervising Bachelor’s or Master’s students while developing expertise in neurodegenerative disease research, molecular biology, circadian biology and biomarker-oriented investigations.
Funding details
This is a full-time, fixed-term doctoral employment for four years. The position provides a monthly salary according to the Faculty’s applicable doctoral student salary scale. Doctoral students are both admitted as students and employed by Lund University, with employee benefits including generous holidays and an occupational pension.
What's required
Applicants must hold a second-cycle degree, have completed at least 240 higher education credits including at least 60 credits at second-cycle level, or possess essentially equivalent knowledge. Applicants should demonstrate good knowledge of neurodegenerative diseases and molecular biology; experience with in vivo and in vitro studies, primer design and RT-PCR optimisation; the ability to work independently and collaboratively; strong written and visual research communication skills; good spoken and written English; an organised and independent approach; experience collaborating on ambitious research projects; and openness to constructive feedback and continued learning. Preference is given to applicants who graduated no more than three years before the application closing date.
How to apply
Apply through the Varbi application portal with a cover letter explaining your interest and suitability, a CV, degree certificate or equivalent, and any relevant additional documents such as transcripts, referee details or recommendation letters.
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Review drafts and confirm requirements with the university.
Professors
Research Group Leader
Sweden
Research Interests
Neuropsychology
Rna-seq
Circadian Rhythm
Neurodegenerative Disease
Biology
ApplyKite TwinLearns as you applyMake your next move.
Prepare your application
Review drafts and confirm requirements with the university.