PhD/MPhil in Development of PET Radiotracers for Neurodegeneration University of Cambridge in United Kingdom

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on programmed axon death , SARM1 , NMNAT2 , and protein design . The project focuses on understanding the mechanism of programmed axon death, an intrinsic axonal death pathway implicated in neurodegenerative disease and injury. The work will use rational protein design to create variant forms of SARM1 or hybrid reporter constructs to study activation, stability, enzyme activity, and post-translational modi...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on retrograde mitochondrial signalling, epigenetic reprogramming, glial toxicity, and neuroinflammation in progressive multiple sclerosis . The project focuses on how mitochondrial dysfunction and mitochondrial stress trigger nuclear signalling and epigenetic changes that may drive astrocytes toward a dysfunctional disease-associated radial glia-like (DARG) phenotype. The work is strongly research-oriented...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Fluid Biomarkers of Inflammation in Frontotemporal Dementia . This project focuses on neuroscience , neurology , neuroinflammation , frontotemporal dementia , and related neurodegenerative disorders, with additional relevance to Alzheimer’s disease , biomarkers , proteomics , neuroimaging , and clinical data analysis. The research aims to characterise inflammation signatures in blood and CSF from people...

Amsterdam UMC is offering a PhD position in spatial proteomics focused on frontotemporal dementia (FTD). The project aims to uncover the molecular and cellular causes of FTD that drive disease onset and early progression, with the long-term goal of supporting evidence-based treatment design. In this PhD project, you will design and execute proteomics studies using human postmortem brain tissue from sporadic FTD patients and human iPSC-derived neurons. The research combines highly innovative sing...

PhD opportunity at Queen's University Belfast in Engineering Bioactive Peptides for Vaginal Microbiome Restoration and Sustained Vaginal Delivery . This funded PhD sits in the School of Biological Sciences and is supported by the NorthWestBio DTP . The project investigates how engineered bioactive peptides can selectively shift disrupted vaginal microbiome models toward a more protective state, with a focus on vaginal microbiome , bioactive peptides , biofilm science , microbiology , epithelial ...