Postdoc Position in Medicinal Chemistry for Piezo1 Inhibitor Discovery Utrecht University in Netherlands

Utrecht University is advertising a postdoc position in medicinal chemistry within the Chemical Biology and Drug Discovery division of the Utrecht Institute for Pharmaceutical Sciences (UIPS), in collaboration with researchers at UMC Utrecht . The project focuses on the discovery and optimization of novel Piezo1 inhibitors for sickle cell disease , combining virtual screening , AI techniques , computational drug discovery , organic synthesis , and chemical biology . The successful candidate will...

Leiden University / Leiden University Medical Center / Leiden Early Drug Discovery and Development (LED3) are advertising a postdoctoral position in medicinal chemistry and chemical biology focused on a synthetic lethality target . The project is described as an exciting collaboration with Sylvie Noordermeer at Leiden University Medical Center, who pioneered the discovery of the synthetic lethal nature of the target. The lab environment is presented as highly collaborative and discovery-oriented...

Leiden University is advertising an open PhD position for Doctoral Candidate 10 in the Marie Skłodowska-Curie Doctoral Network ANA-KIN . The project sits at the intersection of cheminformatics , medicinal chemistry , and cancer drug discovery , with a focus on moving beyond the classic ATP-binding-site approach used by many kinase inhibitors. The research aims to train interdisciplinary researchers to develop experimental and computational tools , modular assays , and workflows for systematicall...

Postdoctoral Fellow opportunity at The University of Hong Kong in the Department of Microbiology, School of Clinical Medicine, for research in antiviral drug discovery and RNA-targeted therapeutics . The project focuses on developing small-molecule approaches to target conserved viral RNA elements. The successful candidate will contribute to viral RNA target analysis, RNA structure modeling, virtual screening, compound prioritization, small-molecule design, assay development, and early-stage dru...

CNRS Research Director Anton Granzhan is recruiting for an 18-month postdoctoral position in bioorganic chemistry and chemical biology at LCBPT (CNRS – Université Paris Cité, Paris, France). The project builds on a recent discovery of small molecules that selectively bind DNA three-way junctions and show toxicity against certain cancer cells. The next stage is to design a new generation of macrocyclic TWJ ligands and heterobifunctional probes to investigate how these molecules act in cells. Suit...