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Christoph Merten

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Postdoctoral position in multiplexed single-cell RNAseq-based antibody discovery EPFL in Switzerland

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Available

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Country

Switzerland

University

EPFL

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Keywords

Cell Biology
Biochemistry
Biomedical Engineering
Biology
Medical Science
Next-generation Sequencing
Microfluidic
Bioinformatic

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About this position

Lab of Biomedical Microfluidics (LBMM) at EPFL is recruiting a postdoctoral researcher for a project on highly multiplexed single-cell RNA-seq-based antibody discovery. The work sits at the intersection of single-cell biology, next-generation sequencing, microfluidics, and translational antibody discovery.

The successful candidate will join a lab that has developed technology platforms in biomedicine and genomics and that combines a technology-development environment on the EPFL campus with a translational lab at the AGORA cancer research center. The project aims to exploit transcriptomic data sets to identify new therapeutic antibodies, with direct interaction with experts in microfluidics and bioinformatics.

The position includes experimental and analytical work across the single-cell discovery pipeline, including optimizing sequencing workflows, sorting cells by FACS, preparing NGS libraries, analyzing data, and helping design screens with bioinformaticians. The advert highlights exposure to custom single-cell microfluidic platforms and a multidisciplinary research setting with clinical connections in Europe and the United States.

The lab also notes its broader ecosystem, including startup spinouts and a strong translational orientation, making this a project for a researcher who wants to work across method development, antibody discovery, and biomedical application.

Funding details

Available

What's required

Postdoctoral applicants should have primary training in single-cell biology, next-generation sequencing, or antibody discovery. Hands-on experience in single-cell analysis and/or antibody discovery is required, with good knowledge of single-cell RNA-seq workflows such as 10x Genomics or DropSeq and experience in flow cytometry. Good knowledge of cell biology and biochemistry is expected. Prior experience in microfluidics is advantageous but not required. Strong communication skills and a highly motivated, interdisciplinary mindset are preferred.

How to apply

Apply only through the online platform. Submit a brief cover letter, a CV with publication list in one PDF together with a research statement, and contact details for three referees.

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Professors

Prof. at EPFL

University Name
Country flag

Switzerland

Research Interests

Cell Biology

Biochemistry

Next-generation Sequencing

Microfluidic

Medical Science