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University of Michigan
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Postdoctoral Research Fellow in Extracellular Vesicle Heterogeneity, Nanomedicine and AI University of Michigan in United States
Degree Level
Postdoc
Field of study
Biomedical Engineering
Funding
Available
Deadline
Dec 8, 2026
Country
United States
University
University of Michigan
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About this position
The University of Michigan’s Michigan Center for Extracellular Nanomedicine (MCEN) is seeking a founding Postdoctoral Research Fellow to build a platform for resolving extracellular vesicle and particle (EVP) heterogeneity. The position spans the School of Dentistry and College of Engineering in Ann Arbor and focuses on understanding the nanoscale packages that cells use to communicate.
The fellow will design, build and validate an integrated EVP platform combining high-resolution separation methods such as asymmetric-flow field-flow fractionation, immunoaffinity and microfluidic sorting with single-particle measurements, including nano-flow cytometry, single-EV imaging and single-vesicle protein and RNA profiling. The platform will be benchmarked to MISEV standards and developed as a shared resource for researchers across medicine, dentistry, engineering, pharmacy and the life sciences.
With supervisors Jae-Won Shin and Sunitha Nagrath, the fellow will establish an independent research direction using EVP subpopulations to develop diagnostic signatures or therapeutic candidates. Potential applications include liquid biopsy for early disease detection and subpopulation-enriched or engineered vesicles for drug delivery and tissue repair in cancer, neurodegeneration and regeneration.
The research also connects single-particle and multi-omic datasets with artificial intelligence and predictive modeling. The fellow will help classify EVP subpopulations and relate particle structure to biological function, while contributing to high-impact manuscripts, interdisciplinary training, shared instrumentation proposals and collaborations with the wider research community.
Funding details
Available
What's required
Applicants must hold a PhD or equivalent degree, including DDS/DMD-PhD or MD-PhD, in biomedical engineering, cell or molecular biology, materials science, chemical engineering, pharmaceutical sciences or a related field, and have at least two first-author peer-reviewed original research papers. Preferred qualifications include experience building, integrating or automating instruments, assays or protocols; handling imaging, flow or omics datasets with quantitative, statistical or computational methods; and communicating across biology, engineering and clinical disciplines. Strong pluses include hands-on extracellular vesicle methods, microfluidics, liquid biopsy, single-particle or label-free analysis, Python or R, machine learning, shared core facility experience or fellowship funding. Three references are required, along with a CV and a vision statement of no more than two pages.
How to apply
Apply through the University of Michigan job portal. Submit a CV, a two-page maximum vision statement addressing how your expertise would shape the EVP heterogeneity platform and the first diagnostic or therapeutic question you would pursue, and contact information for three references. Review begins immediately and continues until the position is filled.
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Make your next move.
Prepare your application
Review drafts and confirm requirements with the university.