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Publisher
source

CNRS

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Postdoctoral Research Position: Autophagy, Stress and Development CNRS in France

Degree Level

Postdoc

Field of study

Biology

Funding

Available

Deadline

Nov 27, 2026

Country flag

Country

France

University

CNRS

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Keywords

Biology
Autophagy
Transcriptional Regulation
Resiliency
Stress Response
Heat Stress
Bioinformatic
Transcriptomic

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About this position

This postdoctoral project at CNRS focuses on how C. elegans adapts to acute, non-lethal thermal stress and why individuals within the same population respond differently. The team has established a stress model that produces two worm subpopulations with distinct outcomes for growth, fertility, and lifespan, and the project aims to uncover the genetic regulatory network and molecular mechanisms underlying this variability.

The work combines experimental biology and bioinformatics. The postdoctoral researcher will run thermal-stress experiments on multiple C. elegans strains, including controls, mutants, and fluorescent reporter lines, and will carry out transcriptomic analyses from sample preparation through to data interpretation. The project places particular emphasis on RNA-based approaches, including RT-qPCR, RNA-Seq, and single-nucleus RNA-seq, to identify regulators of adaptation and links between stress responses and health-related traits.

The researcher will work with the team’s established model system and benefit from the sequencing and bioinformatics platforms of the I2BC, supporting an integrated experimental and computational workflow. The project builds on recent work from the group on autophagy and heat-stress adaptation in C. elegans, and is situated in a collaborative environment with team meetings and consortium interactions.

The postdoctoral scientist will also prepare progress summaries for the project coordinator and present findings during lab and consortium meetings.

Funding details

Available

How to apply

Apply through the official posting link provided. Follow the instructions on the application portal and submit the requested materials before the deadline.

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