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Instituto de Tecnologia Química e Biológica António Xavier – ITQB NOVA
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Postdoctoral Researcher in Advanced Cellular Models, Neuroprotection and Gene Therapy Immune Responses Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa in Portugal
Degree Level
Postdoc
Field of study
Biotechnology
Funding
The position is funded by the Lisboa 2030 Regional Operational Programme through FEDER and Fundação para a Ciência e a Tecnologia. It is a full-time PhD-holder employment position at Level 33 of Portugal's Single Retributive Table, with a 35-hour work week. The project phase is expected to last two years; the contract is for an unspecified term under the applicable Portuguese legal framework.
Deadline
Nov 26, 2026
Country
Portugal
University
Instituto de Tecnologia Química e Biológica António Xavier – ITQB NOVA
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About this position
ITQB NOVA, part of Universidade NOVA de Lisboa, is recruiting a postdoctoral PhD holder to work in Oeiras, Portugal, on the project “Advanced cellular models to reshape the innate immune response to gene therapy vectors.” The research is situated at the intersection of biology, biotechnology and neuroscience.
The researcher will develop and apply advanced mammalian and human neuronal cellular models to investigate neuroprotection, neuronal survival and neurodegeneration in translational contexts. The project includes the development of three-dimensional cell systems such as spheroids and organoids, together with functional and molecular analyses relevant to gene therapy and innate immune responses.
The work will involve experimental cellular and molecular biology, including viability and apoptosis assays, flow cytometry and microscopy. The researcher will contribute to assessing neuroprotective effects and neuronal survival, while helping coordinate experimental activities and potentially supervising students.
The position is hosted in the ITQB NOVA research environment, with collaboration involving iBET. The role offers an opportunity to work in a multidisciplinary and potentially international setting focused on translational biomedical research, advanced model systems and recombinant protein-related applications.
Funding details
The position is funded by the Lisboa 2030 Regional Operational Programme through FEDER and Fundação para a Ciência e a Tecnologia. It is a full-time PhD-holder employment position at Level 33 of Portugal's Single Retributive Table, with a 35-hour work week. The project phase is expected to last two years; the contract is for an unspecified term under the applicable Portuguese legal framework.
What's required
Applicants must hold a PhD in Biology, Biotechnology, Neurosciences, Molecular Biology or a related field, have at least three scientific publications as first author, proven experimental research experience, and a profile oriented toward translational and multidisciplinary research. Specific requirements include experience with mammalian cell culture and human neuronal models; development of 3D cellular models such as spheroids or organoids; cellular and molecular biology techniques including viability assays, apoptosis assays, flow cytometry and microscopy; functional assessment of neuroprotection and neuronal survival; solid knowledge of neurodegeneration and translational models; and experience coordinating experimental activities or supervising students. Strong scientific communication and teamwork skills are required. Experience in international collaborative environments and recombinant protein production and characterization are valued.
How to apply
Combine the detailed CV, motivation letter, two reference contacts and a copy of the PhD certificate into one PDF. Email the file to [email protected] with “029/TRI-PhD/2026” in the subject line.
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