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University of Chicago

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Postdoctoral Scholar in Methyltransferase Biology, Ovarian Cancer, and Tumor Microenvironment The University of Chicago in United States

Degree Level

Postdoc

Field of study

Immunology

Funding

Benefits-eligible, full-time fixed-term postdoctoral position. Compensation follows the NIH NRSA Stipend Scale, with a stated salary range of $63,480–$77,076 per year depending on prior experience. Additional employee benefits are available through the University of Chicago.

Deadline

Nov 28, 2026

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Country

United States

University

University of Chicago

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Keywords

Immunology
Cancer Biology
Biology
Medical Science
Spatial Biology
Tumor Microenvironment
Metastasis
Ovarian Cancer
Epigenetic

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About this position

The University of Chicago’s Ovarian Cancer Laboratory is seeking a Postdoctoral Scholar in the Section of Gynecologic Oncology, Department of Obstetrics and Gynecology, Biological Sciences Division. The research will investigate methyltransferase biology in ovarian cancer, focusing on how metabolic and epigenetic reprogramming in cancer-associated fibroblasts and tumor cells drives immune suppression and metastasis.

The project combines cancer biology, tumor microenvironment research, immunology, epigenetics, cellular metabolism, and translational therapeutics. The postdoctoral researcher will define stromal–tumor–immune interactions that shape ovarian cancer progression and identify therapeutic vulnerabilities with clinical potential. Methods include preclinical mouse tumor models, organoids, spatial and single-cell multi-omics, flow cytometry, metabolic profiling, and cellular and molecular biology assays.

The laboratory, led by Dr. Ernst Lengyel, conducts collaborative bench-to-bedside research aimed at improving outcomes for women with ovarian cancer. Researchers are supported in developing independent ideas, mentoring junior trainees, and preparing for careers in academia, biotechnology, or industry.

Applicants should have a PhD in biochemistry, molecular biology, cancer biology, immunology, or a related field; 3–4 years of hands-on experience with in vivo tumor models; peer-reviewed publications; strong communication skills; and the ability to work independently and collaboratively. Relevant experience in epigenetics, cellular metabolism, tumor microenvironment biology, tumor modeling, multi-omics, or drug development is advantageous.

This is a full-time, fixed-term, benefits-eligible position in Chicago, Illinois. Compensation is $63,480–$77,076 per year, depending on experience, following the NIH NRSA Stipend Scale. The application deadline is November 28, 2026. Applicants should email a CV, research-goals statement, and contact details for two references to [email protected].

Funding details

Benefits-eligible, full-time fixed-term postdoctoral position. Compensation follows the NIH NRSA Stipend Scale, with a stated salary range of $63,480–$77,076 per year depending on prior experience. Additional employee benefits are available through the University of Chicago.

What's required

Applicants must hold a PhD in biochemistry, molecular biology, cancer biology, immunology, or a related field. Required qualifications include 3–4 years of hands-on experience with in vivo tumor models, a strong academic background with peer-reviewed publications, excellent written and verbal communication skills, and the ability to work independently and collaboratively in a multidisciplinary team. Experience in epigenetics, cellular metabolism, and/or tumor microenvironment biology is required or strongly relevant. Preferred expertise includes in vivo and in vitro tumor modeling, spatial and single-cell multi-omics, tumor metabolism and epigenetics, and translational therapeutics or drug development.

How to apply

Submit a curriculum vitae, a statement of research goals, and the names and email addresses of two references. Send application materials to [email protected].

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