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Marcin Poręba

2 months ago

Research Assistant (PhD Student) in Antibody-Drug Conjugates and Matrix Metalloproteinase-Activated Cancer Therapeutics Wrocław University of Science and Technology in Poland

Degree Level

PhD

Field of study

Chemistry

Funding

Available

Deadline

Sep 9, 2026

Country flag

Country

Poland

University

Wrocław University of Scince and Technology

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Keywords

Chemistry
Biomedical Engineering
Biology
Peptide Chemistry
Medical Science
Pharmacy
Cancer Therapy
Bioconjugation
Solid Tumor

About this position

Research Assistant (PhD Student) position at the Wrocław University of Science and Technology, Faculty of Chemistry, in the Department of Biological Chemistry and Bioimaging.

The post is part of the PACMAN project, “Personalized antibody-drug conjugates activated by matrix metalloproteinases for solid tumors,” led by Marcin Poręba (Professor of WUST). The project aims to develop a new generation of antibody-drug conjugates that do not rely on internalization and are instead selectively activated in the extracellular tumor microenvironment by matrix metalloproteinases such as MMP-2, MMP-9, and MMP-14.

The successful candidate will work on the synthesis of antibody-drug and antibody-fluorophore conjugates with different linker types, as well as the physicochemical characterization of the resulting compounds. The role is research-intensive and sits within a translational program aiming toward preclinical validation and, longer term, IND-level documentation and first-in-human progression.

This is a PhD-level research opening (First Stage Researcher, R1) with a full-time contract at 7/8 FTE. The appointment is initially for 12 months, with the possibility of extension for another 18 months after positive evaluation, for a total of 30 months. The advertised salary is PLN 5,393 gross plus additional thirteenth salary.

Eligibility highlights include a Master’s degree in Biotechnology, Chemistry, or a related field, enrolment in the Doctoral School, experience with basic synthetic techniques in chemistry or peptide chemistry, and experience with basic analytical techniques in organic chemistry. Strong English proficiency, teamwork, communication skills, and alignment with the team’s research goals are emphasized in the selection process.

Applicants should submit the required documents by email to [email protected] and include the reference number As16/W3/08/2026_ENG in the subject line. The deadline is 9 September 2026, 23:55 (Europe/Warsaw).

The university also highlights a supportive research environment, opportunities for academic development, teaching, and international cooperation.

Funding details

Available

What's required

Master’s degree in Biotechnology, Chemistry, or a related field; enrolment in the Doctoral School; experience with basic synthetic techniques in chemistry or peptide chemistry; experience with basic analytical techniques in organic chemistry; ability to comply with the non-competition policy under WIB Programme guidelines; excellent English proficiency. Selection also considers relevant scientific and professional experience, previous research activity, scientific achievements such as publications, participation in projects, awards and references, international experience and mobility, teamwork, communication skills, and alignment of development plans with the research team.

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Professors

Prof. of WUST at Wrocław University of Science and Technology

University Name
Country flag

Poland

Research Interests

Pharmacy

Statistics

Medical Science

Biomedical Engineering

Biology