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Alexander Leitner

Senior Scientist / Principal Investigator

ETH Zürich

Switzerland

Research Interests

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Professors in Switzerland Professors in Biochemistry Biochemistry professors in Switzerland

Articles (20)

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2025

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2023

Collaborators (26)

Christian A. Hanke

University of Stuttgart

GERMANY

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Christoph Giese

ETH Zürich

SWITZERLAND

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Ossia M Eichhoff

Senior Scientist

University Hospital of Zurich

SWITZERLAND

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Juri Rappsilber

Technische Universität Berlin

GERMANY

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Verena Paulitschke

Medical University of Vienna

AUSTRIA

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Vikram Panse

SWITZERLAND

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Sebastian Robert Ott

Head of Departmebnt

St. Claraspital

SWITZERLAND

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Julian Harrison

ETH Zürich

SWITZERLAND

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Ezra Peisach

Rutgers University

UNITED STATES

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Jingwei Xu

Tenure-check assistant professor

Westlake University

CHINA

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Estelle Toulme

GERMANY

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Agnieszka Gambus

University of Birmingham

UNITED KINGDOM

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Petr Novak

Charles University

CZECH REPUBLIC

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Carl Kesselman

Professor

University of Southern California

UNITED STATES

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Paola Picotti

Group Leader / Prof.

ETH Zürich

SWITZERLAND

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Pedro Beltrao

Associate Professor

ETH Zürich

SWITZERLAND

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Esben Trabjerg

Københavns Universitet

DENMARK

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Michal Wieczorek

ETH Zurich

SWITZERLAND

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Christoph Hoeller

Associate Professor, Head of Skin Cancer Center

Medical University of Vienna

AUSTRIA

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Stephan Pless

Associate Professor

Københavns Universitet

DENMARK

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Jan Terje Andersen

Group leader

University of Oslo

NORWAY

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Volodymyr Korkhov

ETH Zürich

SWITZERLAND

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Daniel Boehringer

ETH-Bereich Hochschulen

SWITZERLAND

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Soung‐Hun Roh

Seoul National University

SOUTH KOREA

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Andrew Jones

Professor

University of Liverpool

UNITED KINGDOM

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Oscar Vadas

University of Geneva

SWITZERLAND

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Alexander Leitner

Research Interests

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Articles (20)

Substrates bind to residues lining the ring of asymmetrically engaged bacterial proteasome activator Bpa

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

A Roadmap for Improving Reliability and Data Sharing in Crosslinking Mass Spectrometry

CDK-driven phosphorylation of TRAIP is essential for mitotic replisome disassembly and MiDAS

Identification of a direct interaction between the Fab domains of IgG antibodies and human FcRn upon IgG-FcRn complex formation

Structure and assembly of the A-C linker connecting microtubule triplets in centrioles

Mechanistic basis for PYROXD1-mediated protection of the human tRNA ligase complex against oxidative inactivation

A highly sensitive protein-RNA cross-linking mass spectrometry workflow with enhanced structural modeling potential

Characterization of the N- and C-terminal domain interface of the three main apoE isoforms: A combined quantitative cross-linking mass spectrometry and molecular modeling study

Proteomic and structural comparison between cilia from primary ciliary dyskinesia patients with a DNAH5 defect

Structure of the nucleosome-bound human BCL7A

A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle

Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics

Stoichiometry and architecture of the human pyruvate dehydrogenase complex

mzIdentML 1.3.0 – Essential progress on the support of crosslinking and other identifications based on multiple spectra

IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods

An inhibitory segment within G-patch activators tunes Prp43-ATPase activity during ribosome assembly

Specific protein-RNA interactions are mostly preserved in biomolecular condensates

Low-temperature plasma jet treatment generates reactive oxygen species in solution that leads to peptide oxidation and protein aggregation

Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy

Collaborators (26)

Christian A. Hanke

Christoph Giese

Ossia M Eichhoff

Juri Rappsilber

Verena Paulitschke

Vikram Panse

Sebastian Robert Ott

Julian Harrison

Ezra Peisach

Jingwei Xu

Estelle Toulme

Agnieszka Gambus

Petr Novak

Carl Kesselman

Paola Picotti

Pedro Beltrao

Esben Trabjerg

Michal Wieczorek

Christoph Hoeller

Stephan Pless

Jan Terje Andersen

Volodymyr Korkhov

Daniel Boehringer

Soung‐Hun Roh

Andrew Jones

Oscar Vadas

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